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Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96641
Substrate
n/a
EC50
>29910±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose response assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96641
Synonyms:
MLS000585149 | N-(3,4-dihydro-1H-2-benzopyran-1-ylmethyl)-1-(3,4-dimethoxyphenyl)methanimine | N-(3,4-dihydro-1H-isochromen-1-ylmethyl)-1-(3,4-dimethoxyphenyl)methanimine | N-(3,4-dihydro-1H-isochromen-1-ylmethyl)-N-[(1E)-(3,4-dimethoxyphenyl)methylene]amine | SMR000203912 | cid_4458727 | isochroman-1-ylmethyl(veratrylidene)amine
Type:
Small organic molecule
Emp. Form.:
C19H21NO3
Mol. Mass.:
311.3749
SMILES:
COc1ccc(\C=N\CC2OCCc3ccccc23)cc1OC
Structure:
Search PDB for entries with ligand similarity: