Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM96641
Substrate
n/a
IC50
511.54±n/a nM
Citation
 PubChem, PC Counterscreen for agonists of the human trace amine associated receptor 1 (hTAAR1): Fluorescence-based cell-based high throughput dose response assay to identify hTAAR1 agonist that also desensitize TAAR1 receptor response. PubChem Bioassay (2013)[AID] 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1
Type:
PROTEIN
Mol. Mass.:
39107.47
Organism:
Homo sapiens (Human)
Description:
ChEMBL_792734
Residue:
339
Sequence:
MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGGCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNGISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
  
Inhibitor
Name:
BDBM96641
Synonyms:
MLS000585149 | N-(3,4-dihydro-1H-2-benzopyran-1-ylmethyl)-1-(3,4-dimethoxyphenyl)methanimine | N-(3,4-dihydro-1H-isochromen-1-ylmethyl)-1-(3,4-dimethoxyphenyl)methanimine | N-(3,4-dihydro-1H-isochromen-1-ylmethyl)-N-[(1E)-(3,4-dimethoxyphenyl)methylene]amine | SMR000203912 | cid_4458727 | isochroman-1-ylmethyl(veratrylidene)amine
Type:
Small organic molecule
Emp. Form.:
C19H21NO3
Mol. Mass.:
311.3749
SMILES:
COc1ccc(\C=N\CC2OCCc3ccccc23)cc1OC
Structure:
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