Reaction Details Report a problem with these data
Target
Guanine nucleotide-binding protein subunit alpha-15
Ligand
BDBM96914
Substrate
n/a
EC50
>29934±n/a nM
Citation
 PubChem, PC Counterscreen for antagonists of the human trace amine associated receptor 1 (TAAR1): Fluorescence-based cell-based high throughput dose reponse assay to identify nonselective Ga16 agonists PubChem Bioassay (2013)[AID] 
Target
Name:
Guanine nucleotide-binding protein subunit alpha-15
Synonyms:
G protein alpha 16 | G-protein subunit alpha-16 | G-protein subunit alpha-16 (G alpha-16) | GNA15 | GNA15_HUMAN | GNA16 | Guanine nucleotide-binding protein subunit alpha-15 [Y147C]
Type:
Protein
Mol. Mass.:
43577.62
Organism:
Homo sapiens (Human)
Description:
P30679
Residue:
374
Sequence:
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQDPYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL
  
Inhibitor
Name:
BDBM96914
Synonyms:
1-[(E)-[1-(4-chlorophenyl)-2,5-dimethyl-3-pyrrolyl]methylideneamino]-3-ethylthiourea | 1-[(E)-[1-(4-chlorophenyl)-2,5-dimethyl-pyrrol-3-yl]methyleneamino]-3-ethyl-thiourea | 1-[(E)-[1-(4-chlorophenyl)-2,5-dimethyl-pyrrol-3-yl]methylideneamino]-3-ethyl-thiourea | 1-[(E)-[1-(4-chlorophenyl)-2,5-dimethylpyrrol-3-yl]methylideneamino]-3-ethylthiourea | MLS001033073 | SMR000385529 | cid_6904296
Type:
Small organic molecule
Emp. Form.:
C16H19ClN4S
Mol. Mass.:
334.867
SMILES:
CCNC(=S)NN=Cc1cc(C)n(c1C)-c1ccc(Cl)cc1 |w:6.5|
Structure:
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