Reaction Details Report a problem with these data
Target
Tachykinin-3
Ligand
BDBM97475
Substrate
n/a
Meas. Tech.
Human NK3 Receptor Binding Assay
pH
7.4±n/a
IC50
23±0.0 nM
Comments
extracted
Citation
 Ikeura, Y; Shirai, J; Sugiyama, H; Nishikimi, Y; Kamei, T; Sakauchi, N Nitrogen-containing heterocyclic compound and use thereof US Patent  US8470816 Publication Date 6/25/2013 
Target
Name:
Tachykinin-3
Synonyms:
NKNB | TAC3 | TKNK_HUMAN | Tachykinin receptor 3 (NK3)
Type:
Protein
Mol. Mass.:
13439.23
Organism:
Homo sapiens (Human)
Description:
Q9UHF0
Residue:
121
Sequence:
MRIMLLFTAILAFSLAQSFGAVCKEPQEEVVPGGGRSKRDPDLYQLLQRLFKSHSSLEGLLKALSQASTDPKESTSPEKRDMHDFFVGLMGKRSVQPDSPTDVNQENVPSFGILKYPPRAE
  
Inhibitor
Name:
BDBM97475
Synonyms:
US8470816, 30
Type:
Small molecule
Emp. Form.:
C27H30Cl3N3O3
Mol. Mass.:
550.904
SMILES:
CN([C@@H]1CCN(CC1c1ccc(Cl)c(Cl)c1)C(=O)C1CCN(CC1)C(C)=O)C(=O)c1ccc(Cl)cc1 |r|
Structure:
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