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Target
Kallikrein-7
Ligand
BDBM100160
Substrate
n/a
EC50
>69562±n/a nM
Citation
 PubChem, PC Fluorescence Intensity-based biochemical primary high throughput dose response assay to identify activators of kallikrein-7 (K7) zymogen PubChem Bioassay (2013)[AID] 
Target
Name:
Kallikrein-7
Synonyms:
KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein
Type:
PROTEIN
Mol. Mass.:
27535.05
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469257
Residue:
253
Sequence:
MARSLLLPLQILLLSLALETAGEEAQGDKIIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRRAQRIKASKSFRHPGYSTQTHVNDLMLVKLNSQARLSSMVKKVRLPSRCEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDSKKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMKKHR
  
Inhibitor
Name:
BDBM100160
Synonyms:
6-chloranyl-4-methyl-7-(2-morpholin-4-yl-2-oxidanylidene-ethoxy)chromen-2-one | 6-chloro-4-methyl-7-(2-morpholin-4-yl-2-oxoethoxy)chromen-2-one | 6-chloro-4-methyl-7-[2-(4-morpholinyl)-2-oxoethoxy]-1-benzopyran-2-one | 6-chloro-7-(2-keto-2-morpholino-ethoxy)-4-methyl-coumarin | MLS002248714 | SMR001316174 | cid_4791089
Type:
Small organic molecule
Emp. Form.:
C16H16ClNO5
Mol. Mass.:
337.755
SMILES:
Cc1cc(=O)oc2cc(OCC(=O)N3CCOCC3)c(Cl)cc12
Structure:
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