Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM129505
Substrate
n/a
Meas. Tech.
Radioligand Binding
pH
7.4±n/a
Temperature
310.15±n/a K
Ki
0.9±n/a nM
Comments
extracted
Citation
 Galley, G; Norcross, RD; Pflieger, P Heterocyclic amine derivatives US Patent  US8802673 Publication Date 8/12/2014 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mouse
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM129505
Synonyms:
US8802673, 147
Type:
Small organic molecule
Emp. Form.:
C18H18N4O2
Mol. Mass.:
322.3611
SMILES:
C1CO[C@H](CN1)c1ccc(Nc2ncc(cn2)-c2ccco2)cc1 |r|
Structure:
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