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Target
Delta-type opioid receptor
Ligand
BDBM133906
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Ki
20971±n/a nM
Comments
extracted
Citation
 Fuchino, K; Goehring, RR; Shao, B; Taoda, Y; Tsuno, N; Whitehead, JW; Yao, J Substituted-quinoxaline-type piperidine compounds and the uses thereof US Patent  US8846929 Publication Date 9/30/2014 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM133906
Synonyms:
US8846929, 79
Type:
Small organic molecule
Emp. Form.:
C25H36N4O4
Mol. Mass.:
456.5777
SMILES:
OCC(O)CNC(=O)c1nc2ccccc2n(C2CCN(CC2)C2CCCCCCC2)c1=O
Structure:
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