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Target
Serine/threonine-protein kinase pim-2
Ligand
BDBM141326
Substrate
n/a
Meas. Tech.
Kinase Assay
pH
3±n/a
IC50
3599±n/a nM
Comments
extracted
Citation
 Caldarelli, M; Casuscelli, F; Donati, D; Mirizzi, D; Quartieri, F; Silvagni, M Tricyclic derivatives, process for their preparation and their use as kinase inhibitors US Patent  US8916577 Publication Date 12/23/2014 
Target
Name:
Serine/threonine-protein kinase pim-2
Synonyms:
PIM2 | PIM2_HUMAN | Pim-2h | Serine/threonine-protein kinase (PIM2) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase pim-2 (PIM2)
Type:
Serine/threonine-protein kinase
Mol. Mass.:
34185.93
Organism:
Homo sapiens (Human)
Description:
Q9P1W9
Residue:
311
Sequence:
MLTKPLQGPPAPPGTPTPPPGGKDREAFEAEYRLGPLLGKGGFGTVFAGHRLTDRLQVAIKVIPRNRVLGWSPLSDSVTCPLEVALLWKVGAGGGHPGVIRLLDWFETQEGFMLVLERPLPAQDLFDYITEKGPLGEGPSRCFFGQVVAAIQHCHSRGVVHRDIKDENILIDLRRGCAKLIDFGSGALLHDEPYTDFDGTRVYSPPEWISRHQYHALPATVWSLGILLYDMVCGDIPFERDQEILEAELHFPAHVSPDCCALIRRCLAPKPSSRPSLEEILLDPWMQTPAEDVPLNPSKGGPAPLAWSLLP
  
Inhibitor
Name:
BDBM141326
Synonyms:
US8916577, 67
Type:
Small organic molecule
Emp. Form.:
C23H28N8O
Mol. Mass.:
432.5214
SMILES:
CN1CCN(CC1)c1ccc(Nc2ncc3CCCc4c(nn(C)c4-c3n2)C(N)=O)cc1
Structure:
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