Reaction Details
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Histamine oxidase
Ligand
BDBM185657
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.2±n/a
Temperature
303.15±n/a K
IC50
3500000±n/a nM
Comments
extracted
More Info.:
Target
Name:
Histamine oxidase
Synonyms:
AMOH_ARTGO | Amine oxidase (AGAO)
Type:
Enzyme
Mol. Mass.:
75087.19
Organism:
Arthrobacter globiformis
Description:
Q59118
Residue:
684
Sequence:
MTLQTTPSTPLVQDPPVPATLVHAAAQHPLEQLSAEEIHEARRILAEAGLVGESTRFAYLGLIEPPKTTRQGDVTGAARLVRAMLWDAAQSRSLDVRLSLATGLVVDRRELNPEADGQLPVLLEEFGIIEDILSEDPQWNAALTARGLTPAQVRVAPLSAGVFEYGNEEGKRLLRGLGFRQDHPADHPWAHPIDGLVAFVDVENRRVNHLIDDGPVPVPEVNGNYTDPAIRGELRTDLLPIEIMQPEGPSFTLEGNHLSWAGWDLRVGFDAREGLVLHQLHHSHKGRRRPVIHRASISEMVVPYGDPSPYRSWQNYFDSGEYLVGRDANSLRLGCDCLGDITYMSPVVADDFGNPRTIENGICIHEEDAGILWKHTDEWAGSDEVRRNRRLVVSFFTTVGNYDYGFYWYLYLDGTIEFEAKATGIVFTAALPDKDYAYASEIAPGLGAPYHQHLFSARLDMMIDGDANRVEELDLVRLPKGPGNPHGNAFTQKRTLLARESEAVRDADGAKGRVWHISNPDSLNHLGHPVGYTLYPEGNPTLAMADDSSIASRAAFARHHLWVTRHAEEELYAAGDFVNQHPGGAVLPAYVAQDRDIDGQDLVVWHSFGLTHFPRPEDWPIMPVDTTGFTLKPHGFFDENPTLNVPSSAAGHCGTGSEREHAAPGGTAVGHSGPDTGGQGHCGH
Inhibitor
Name:
BDBM185657
Synonyms:
US9161922, Table 3, Compound 2
Type:
Small organic molecule
Emp. Form.:
C12H20N4O4
Mol. Mass.:
284.3116
SMILES:
CCOC(=O)CNC(=O)CNC(=O)C(N)CC#CCN
Structure:
