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Target
Glucagon-like peptide 1 receptor
Ligand
BDBM190076
Substrate
n/a
Meas. Tech.
cAMP Functional Assay
EC50
142±n/a nM
Citation
 Mjalli, AM; Behme, C; Christen, DP; Gohimukkula, DR; Polisetti, DR; Quada, Jr., JC; Freeman, JL; Bondlela, M; Guzel, M; Yarragunta, RR; Andrews, RC; Kalpathy, S; Davis, ST; Yokum, TS Substituted azoanthracene derivatives and intermediates for preparation thereof US Patent  US9175003 Publication Date 11/3/2015 
Target
Name:
Glucagon-like peptide 1 receptor
Synonyms:
GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1)
Type:
Enzyme
Mol. Mass.:
53035.78
Organism:
Homo sapiens (Human)
Description:
P43220
Residue:
463
Sequence:
MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDLFCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPWRDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIHLNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRNSNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLLGTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERWRLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
  
Inhibitor
Name:
BDBM190076
Synonyms:
US9175003, 270
Type:
Small organic molecule
Emp. Form.:
C47H43Cl2N5O7
Mol. Mass.:
860.78
SMILES:
Cc1cc(C(=O)N2Cc3cc4O[C@H](COc4cc3C[C@H]2C(=O)N[C@@H](Cc2ccc(cc2)-c2ccnc(C)c2C)C(O)=O)c2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)n(C)n1 |r|
Structure:
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