Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM190642
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
310.15±n/a K
Ki
8.2±n/a nM
Comments
extracted
Citation
 Galley, G; Goergler, A; Norcross, R; Pflieger, P Morpholine compounds and uses thereof US Patent  US9181230 Publication Date 11/10/2015 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_MOUSE | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mus musculus (Mouse)
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM190642
Synonyms:
US9181230, 48 | US9181230, 50
Type:
Small organic molecule
Emp. Form.:
C16H14F3N3O
Mol. Mass.:
321.2971
SMILES:
FC(F)(F)c1cnc2[nH]c3ccc(cc3c2c1)[C@@H]1CNCCO1 |r|
Structure:
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