Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM190635
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
310.15±n/a K
Ki
4.3±n/a nM
Comments
extracted
Citation
 Galley, G; Goergler, A; Norcross, R; Pflieger, P Morpholine compounds and uses thereof US Patent  US9181230 Publication Date 11/10/2015 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1
Type:
Enzyme
Mol. Mass.:
38034.73
Organism:
Rattus norvegicus (Rat)
Description:
Q923Y9
Residue:
332
Sequence:
MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWLLHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDRYYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRGCFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQSKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMVYAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM190635
Synonyms:
US9181230, 41
Type:
Small organic molecule
Emp. Form.:
C19H17F2N3O
Mol. Mass.:
341.3546
SMILES:
Fc1ccc(cc1)-c1cc(n[nH]1)-c1ccc(cc1F)[C@@H]1CNCCO1 |r|
Structure:
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