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Target
Beta-lactamase
Ligand
BDBM212441
Substrate
n/a
Meas. Tech.
Beta-Lactamase Enzyme Inhibition Assay
pH
7±n/a
Temperature
303.15±n/a K
IC50
950±n/a nM
Comments
extracted
Citation
 Abe, T; Okue, M; Sakamaki, Y Optically active diazabicyclooctane derivatives and process for preparing the same US Patent  US8772490 Publication Date 7/8/2014 
Target
Name:
Beta-lactamase
Synonyms:
AMPC_PSEAE | ampC | beta-Lactamase
Type:
Enzyme
Mol. Mass.:
43406.87
Organism:
Pseudomonas aeruginosa (PAO1)
Description:
P24735
Residue:
397
Sequence:
MRDTRFPCLCGIAASTLLFATTPAIAGEAPADRLKALVDAAVQPVMKANDIPGLAVAISLKGEPHYFSYGLASKEDGRRVTPETLFEIGSVSKTFTATLAGYALTQDKMRLDDRASQHWPALQGSRFDGISLLDLATYTAGGLPLQFPDSVQKDQAQIRDYYRQWQPTYAPGSQRLYSNPSIGLFGYLAARSLGQPFERLMEQQVFPALGLEQTHLDVPEAALAQYAQGYGKDDRPLRVGPGPLDAEGYGVKTSAADLLRFVDANLHPERLDRPWAQALDATHRGYYKVGDMTQGLGWEAYDWPISLKRLQAGNSTPMALQPHRIARLPAPQALEGQRLLNKTGSTNGFGAYVAFVPGRDLGLVILANRNYPNAERVKIAYAILSGLEQQGKVPLKR
  
Inhibitor
Name:
BDBM212441
Synonyms:
US8772490, TAZ
Type:
Small organic molecule
Emp. Form.:
C10H11N4NaO5S
Mol. Mass.:
322.273
SMILES:
CC1(Cn2ccnn2)[C@H](N2C(CC2=O)S1(=O)=O)C(=O)O[Na] |r|
Structure:
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