Reaction Details Report a problem with these data
Target
Galectin-7
Ligand
BDBM223992
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
Temperature
277.15±0 K
Kd
8.6e+4± 3.1e+4 nM
Citation
 Dion, J; Deshayes, F; Storozhylova, N; Advedissian, T; Lambert, A; Viguier, M; Tellier, C; Dussouy, C; Poirier, F; Grandjean, C Lactosamine-Based Derivatives as Tools to Delineate the Biological Functions of Galectins: Application to Skin Tissue Repair. Chembiochem 18:782-789 (2017) [PubMed]  Article 
Target
Name:
Galectin-7
Synonyms:
Gal-7 | HKL-14 | LEG7_HUMAN | LGALS7 | PI7 | PIG1 | p53-induced gene 1 protein
Type:
Galactoside-binding protein
Mol. Mass.:
15077.89
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
136
Sequence:
MSNVPHKSSLPEGIRPGTVLRIRGLVPPNASRFHVNLLCGEEQGSDAALHFNPRLDTSEVVFNSKEQGSWGREERGPGVPFQRGQPFEVLIIASDDGFKAVVGDAQYHHFRHRLPLARVRLVEVGGDVQLDSVRIF
  
Inhibitor
Name:
BDBM223992
Synonyms:
4-O-[3-O-(3-methoxybenzyl)-β-D-galactopyranosyl)]-1-azido-1,2-dideoxy-2-(3-methoxybenzamido)-β-D-glucopyranose (1)
Type:
Small organic molecule
Emp. Form.:
C28H36N4O12
Mol. Mass.:
620.605
SMILES:
COc1cccc(COC2[C@@H](O)C(CO)O[C@@H](O[C@@H]3C(CO)O[C@@H](N=[N+]=[N-])C(NC(=O)c4cccc(OC)c4)C3O)C2O)c1 |r|
Structure:
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