Reaction Details Report a problem with these data
Target
Siderophore-binding protein
Ligand
BDBM239165
Substrate
n/a
Meas. Tech.
CA Inhibition Assay
pH
7.5±n/a
Temperature
298.15±n/a K
Ki
4.8e+2±n/a nM
Comments
extracted
Citation
 Maresca, A; Vullo, D; Scozzafava, A; Manole, G; Supuran, CT Inhibition of the ß-class carbonic anhydrases from Mycobacterium tuberculosis with carboxylic acids. J Enzyme Inhib Med Chem 28:392-6 (2013) [PubMed]  Article 
Target
Name:
Siderophore-binding protein
Synonyms:
β-Carbonic anhydrase 3 (CA 3)
Type:
Enzyme
Mol. Mass.:
17663.22
Organism:
Mycobacterium tuberculosis
Description:
n/a
Residue:
174
Sequence:
MPLFSFEGRSPRIDPTAFVAPTATLIGDVTIEAGASVWFNAVLRGDYAPVVVREGANVQDGAVLHAPPGIPVDIGPGATVAHLCVIHGVHVGSEALIANHATVLDGAVIGARCMIAAGALVVAGTQIPAGMLVTGAPAKVKGPIEGTGAEMWVNVNPQAYRDLAARHLAGLEPM
  
Inhibitor
Name:
BDBM239165
Synonyms:
4-Acetamidobenzoic acid (4)
Type:
Small organic molecule
Emp. Form.:
C9H9NO3
Mol. Mass.:
179.1727
SMILES:
CC(=O)Nc1ccc(cc1)C(O)=O
Structure:
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