Reaction Details Report a problem with these data
Target
Alpha-carbonic anhydrase
Ligand
BDBM62319
Substrate
n/a
Meas. Tech.
CA Inhibition Assay
pH
7.5±n/a
Temperature
298.15±n/a K
Ki
560000±n/a nM
Comments
extracted
Citation
 Maresca, A; Vullo, D; Scozzafava, A; Supuran, CT Inhibition of the alpha- and beta-carbonic anhydrases from the gastric pathogen Helycobacter pylori with anions. J Enzyme Inhib Med Chem 28:388-91 (2013) [PubMed]  Article 
Target
Name:
Alpha-carbonic anhydrase
Synonyms:
α-Carbonic anhydrase (αCA)
Type:
Enzyme
Mol. Mass.:
28382.59
Organism:
Helicobacter pylori
Description:
J0J440
Residue:
247
Sequence:
MKKTFLIALALAASLIGAENTKWDYKNKENGPHRWDKLHKDFEVCKSGKSQSPINIEHYYHTQDKTDLQFKYAASKPKAVFFTHHTLKASFEPTNHINYRGHDYVLDNVHFHAPMEFLINNKTRPLSAHFVHKDAKGRLLVLAIGFEEGKENPNLDPILEDIQKKQNFKEVALDAFLPKTINYYHFNGSLTAPPCTEGVAWFVIEEPLEVSAKQLAEIKKRMKNSPNQRPVQPDYNTVIIKSSAETR
  
Inhibitor
Name:
BDBM62319
Synonyms:
borate (B4O7 2-) | tetraborate
Type:
n/a
Emp. Form.:
B4O7
Mol. Mass.:
155.241
SMILES:
[O-]B1OB2OB([O-])OB(O1)O2
Structure:
Search PDB for entries with ligand similarity: