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Target
Prostaglandin F2-alpha receptor
Ligand
BDBM168294
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
298.15±n/a K
IC50
42±0.0 nM
Comments
extracted
Citation
 PubChem, PC; deLong, MA; McIver, JM; Youngquist, RS Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives US Patent  US9675539 Publication Date 6/13/2017 
Target
Name:
Prostaglandin F2-alpha receptor
Synonyms:
PF2R_HUMAN | PGF receptor | PGF2 alpha receptor | PGF2-alpha receptor | PTGFR | Prostaglandin F | Prostanoid FP receptor
Type:
Enzyme
Mol. Mass.:
40072.29
Organism:
Homo sapiens (Human)
Description:
P43088
Residue:
359
Sequence:
MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST
  
Inhibitor
Name:
BDBM168294
Synonyms:
US9675539, 1-1
Type:
Small organic molecule
Emp. Form.:
C22H33O6P
Mol. Mass.:
424.4676
SMILES:
CP(O)(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\C(O)COc1ccccc1 |r|
Structure:
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