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Target
Neuraminidase
Ligand
BDBM482718
Substrate
n/a
Meas. Tech.
Activity assay for influenza virus neuraminidase
IC50
5.5±n/a nM
Citation
 Zhang, J; Wang, K; Liu, Y; Li, D Cyclohexene compounds and use thereof US Patent  US10919856 Publication Date 2/16/2021 
Target
Name:
Neuraminidase
Synonyms:
Influenza A Virus Neuraminidase | NA | NRAM_I67A0 | Neuraminidase A
Type:
Enzyme
Mol. Mass.:
52132.25
Organism:
Influenza A virus (A/Tokyo/3/67(H2N2))
Description:
P06820
Residue:
469
Sequence:
MNPNQKIITIGSVSLTIATVCFLMQIAILVTTVTLHFKQHECDSPASNQVMPCEPIIIERNITEIVYLNNTTIEKEICPKVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPVKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLAGSAQHVEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDRSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKDLRSGYETFKVIGGWSTPNSKSQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGRKQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
  
Inhibitor
Name:
BDBM482718
Synonyms:
US10919856, Example 3
Type:
Small organic molecule
Emp. Form.:
C16H27N3O5
Mol. Mass.:
341.4027
SMILES:
CC(=O)N[C@@H]1[C@@H](N)CC(OC=O)=C[C@H]1N1CCC[C@H](C1)OCCO |r,c:11|
Structure:
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