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Target
Neuraminidase [H274Y]
Ligand
BDBM482724
Substrate
n/a
Meas. Tech.
Activity assay for influenza virus neuraminidase
IC50
5.5±n/a nM
Citation
 Zhang, J; Wang, K; Liu, Y; Li, D Cyclohexene compounds and use thereof US Patent  US10919856 Publication Date 2/16/2021 
Target
Name:
Neuraminidase [H274Y]
Synonyms:
NA | NRAM_I67A0 | Neuraminidase A (H274Y)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52157.78
Organism:
Influenza A virus (A/Tokyo/3/67(H2N2))
Description:
P06820[H274Y]
Residue:
469
Sequence:
MNPNQKIITIGSVSLTIATVCFLMQIAILVTTVTLHFKQHECDSPASNQVMPCEPIIIERNITEIVYLNNTTIEKEICPKVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPVKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLAGSAQYVEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDRSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKDLRSGYETFKVIGGWSTPNSKSQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGRKQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
  
Inhibitor
Name:
BDBM482724
Synonyms:
US10919856, Example 9
Type:
Small organic molecule
Emp. Form.:
C19H32N4O6
Mol. Mass.:
412.4806
SMILES:
CN(C)C(=O)OCCO[C@H]1CCCN(C1)[C@@H]1C=C(C[C@H](N)[C@H]1NC(C)=O)C(O)=O |r,c:17|
Structure:
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