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Target
Neuraminidase [H274Y]
Ligand
BDBM482725
Substrate
n/a
Meas. Tech.
Activity assay for influenza virus neuraminidase
IC50
5.5±n/a nM
Citation
 Zhang, J; Wang, K; Liu, Y; Li, D Cyclohexene compounds and use thereof US Patent  US10919856 Publication Date 2/16/2021 
Target
Name:
Neuraminidase [H274Y]
Synonyms:
NA | NRAM_I67A0 | Neuraminidase A (H274Y)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52157.78
Organism:
Influenza A virus (A/Tokyo/3/67(H2N2))
Description:
P06820[H274Y]
Residue:
469
Sequence:
MNPNQKIITIGSVSLTIATVCFLMQIAILVTTVTLHFKQHECDSPASNQVMPCEPIIIERNITEIVYLNNTTIEKEICPKVVEYRNWSKPQCQITGFAPFSKDNSIRLSAGGDIWVTREPYVSCDPVKCYQFALGQGTTLDNKHSNDTVHDRIPHRTLLMNELGVPFHLGTRQVCIAWSSSSCHDGKAWLHVCITGDDKNATASFIYDGRLVDSIGSWSQNILRTQESECVCINGTCTVVMTDGSASGRADTRILFIEEGKIVHISPLAGSAQYVEECSCYPRYPGVRCICRDNWKGSNRPVVDINMEDYSIDSSYVCSGLVGDTPRNDDRSSNSNCRNPNNERGTQGVKGWAFDNGNDLWMGRTISKDLRSGYETFKVIGGWSTPNSKSQINRQVIVDSDNRSGYSGIFSVEGKSCINRCFYVELIRGRKQETRVWWTSNSIVVFCGTSGTYGTGSWPDGANINFMPI
  
Inhibitor
Name:
BDBM482725
Synonyms:
US10919856, Example 10
Type:
Small organic molecule
Emp. Form.:
C21H34N4O7
Mol. Mass.:
454.5173
SMILES:
CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1N1CCC[C@@H](C1)OCCOC(=O)N1CCOCC1)C(O)=O |r,c:8|
Structure:
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