| Assay Method Information | |
| | PTP1B Inhibition Assay |
| Description: | Hydrolysis of substrate p-nitrophenyl phosphate was monitored on a 96-well microplate reader. Concentrations of PTP1B inhibitors that resulted in 50% reduction of enzyme activity (IC50) were derived by fitting reaction rates obtained in the presence and absence of compounds. |
| Affinity data for this assay | |
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