| Assay Method Information | |
| | Aurora Kinase Inhibition Assay |
| Description: | The compounds were tested for their ability to inhibit the phosphorylation of serine 10 of histone-H3 by purified recombinant murine Aurora-A enzyme. The phosphorylation of serine 10 was detected colorimetrically using Phospho-Histone H3 (Ser10) (6G3) Mouse mAb (9706, Cell Signaling Technologies, Danvers, MA). |
| Affinity data for this assay | |
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