Assay Method Information | |
| ChEMBL_1722131 (CHEMBL4137131) |
Description: | Binding affinity to human recombinant N-terminal His6-tagged SOS1 (564 to 1049 residues) expressed in BL21-RIL Escherichia coli assessed as SOS1-RAS complex formation by measuring exchange of GTP to BODIPY-GDP measured every 3 secs for 30 mins by fluorescence polarization assay |
Affinity data for this assay | |
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