Assay Method Information

Assay Name:  ChEMBL_1738553 (CHEMBL4154303)
Description:  Inhibition of human Top1B expressed in Top1B deficient Saccharomyces cerevisiae EKY3 assessed as decrease in relaxation of supercoiled pSK DNA preincubated for 15 mins followed by DNA addition and measured after 1 to 16 mins by agarose gel electrophoresis
Affinity data for this assay
 

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