| Assay Method Information | |
| | ChEMBL_2223229 (CHEMBL5136563) |
| Description: | Inhibition of recombinant biotinylated KRAS G12D mutant (unknown origin) assessed as inhibition of SOS-catalyzed nucleotide exchange preincubated for 60 mins followed by addition of human SOS protein and unlabeled GTP and measured after 60 mins by TR-FRET analysis |
| Affinity data for this assay | |
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