| Assay Method Information | |
| | ChEMBL_2262795 (CHEMBL5217806) |
| Description: | Inhibition of NLRP3 inflammasome activation in LPS and nigericin-stimulated human PBMC cells assessed as reduction in IL-1beta release preincubated with LPS for 3 hrs followed by compound addition for 30 mins and further stimulated with nigericin for 1.5 hrs by ELISA analysis |
| Affinity data for this assay | |
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