| Assay Method Information | |
| | ChEMBL_1669001 (CHEMBL4018889) |
| Description: | Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as potentiation of neuropeptide Y induced-calcium flux by measuring neuropeptide Y EC50 at 30 uM treated at 20 secs post baseline detection followed by addition of neuropeptide Y after 140 secs by Fluo2-AM fluorescent dye based-assay (Rvb = 5.2 nM) |
| Affinity data for this assay | |
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