| Assay Method Information | |
| | ChEMBL_1988245 (CHEMBL4621792) |
| Description: | Agonist activity at His6-tagged-human SOS1 catalytic domain (564 to 1049 residues) expressed in Escherichia coli BL21-CodonPlus-RIPL cells assessed as increase in SOS1-mediated GDP/GTP nucleotide exchange upon K-Ras G12D mutant (1 to 169 residues) by BODIPY-GDP assay |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |