Assay Method Information

Assay Name:  ChEMBL_2116923 (CHEMBL4825989)
Description:  Inhibition of P-gp (unknown origin) expressed in MCF7 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity by measuring reduction in paclitaxel EC50 at 50 nM incubated for 72 hrs in presence of paclitaxel by SRB assay (Rvb = 11.5 nM)
Affinity data for this assay
 

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