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Found 1533 for UniProtKB: E9PBH0
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50381716(ABT-348 | ILORASERTIB | US8722890, 1 | US8722890, ...)
Affinity DataKi:  0.794nMAssay Description:Inhibition of PDGFRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50237710(4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifl...)
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM13530(4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[...)
In DepthDetails ArticlePubMedDrugBank

TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50388873(CHEMBL1964441)
Affinity DataKi:  2.5nMAssay Description:Inhibition of PDGFRAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507056((Z)-Methyl 3-(((4-((2-(dimethylamino)ethoxy)carbam...)
Affinity DataKi:  4.57nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM531233((Z)-Methyl 3-(((4-(4-(2-((2-hydroxyethyl)amino)-2-...)
Affinity DataKi:  5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445224(US10669235, Example 15)
Affinity DataKi:  5nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445228(US10669235, Example 19 | US11208381, Example 19)
Affinity DataKi:  6.55nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445228(US10669235, Example 19 | US11208381, Example 19)
Affinity DataKi:  6.55nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507090(US11046672, Example 39)
Affinity DataKi:  6.71nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  6.86nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445255(US10669235, Example 46 | US11208381, Example 46)
Affinity DataKi:  6.86nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  7.38nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445241(US10669235, Example 32 | US11208381, Example 32)
Affinity DataKi:  7.38nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  7.53nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445247(US10669235, Example 38 | US11208381, Example 38)
Affinity DataKi:  7.53nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507073(US11046672, Example 22)
Affinity DataKi:  7.54nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445226(US10669235, Example 17 | US11208381, Example 17)
Affinity DataKi:  7.81nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445226(US10669235, Example 17 | US11208381, Example 17)
Affinity DataKi:  7.81nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445216(US10669235, Example 7 | US11208381, Example 7)
Affinity DataKi:  7.82nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445216(US10669235, Example 7 | US11208381, Example 7)
Affinity DataKi:  7.82nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445218(US10669235, Example 9 | US11208381, Example 9)
Affinity DataKi:  8.36nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445218(US10669235, Example 9 | US11208381, Example 9)
Affinity DataKi:  8.36nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445209(US10669235, Nintedanib)
Affinity DataKi:  8.40nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  8.40nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)
Affinity DataKi:  8.40nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507082(US11046672, Example 31)
Affinity DataKi:  8.74nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507057((Z)-Methyl 5-methyl-3-(((4-((2-(4-methylpiperazin-...)
Affinity DataKi:  8.80nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507058((Z)-Methyl 3-(((4-((2-(4-(2-hydroxyethyl)piperazin...)
Affinity DataKi:  8.80nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445242(US10669235, Example 33 | US11208381, Example 33)
Affinity DataKi:  8.89nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445242(US10669235, Example 33 | US11208381, Example 33)
Affinity DataKi:  8.89nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445257(US10669235, Example 48 | US11208381, Example 48)
Affinity DataKi:  8.92nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445257(US10669235, Example 48 | US11208381, Example 48)
Affinity DataKi:  8.92nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507078(US11046672, Example 27)
Affinity DataKi:  9.11nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507080(US11046672, Example 29)
Affinity DataKi:  9.33nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507081(US11046672, Example 30)
Affinity DataKi:  9.37nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445230(US10669235, Example 21 | US11208381, Example 21)
Affinity DataKi:  9.38nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445230(US10669235, Example 21 | US11208381, Example 21)
Affinity DataKi:  9.38nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445215(US10669235, Example 6 | US11208381, Example 6)
Affinity DataKi:  9.41nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445215(US10669235, Example 6 | US11208381, Example 6)
Affinity DataKi:  9.41nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507093(US11046672, Example 42)
Affinity DataKi:  9.62nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445231(US10669235, Example 22 | US11208381, Example 22)
Affinity DataKi:  9.75nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445231(US10669235, Example 22 | US11208381, Example 22)
Affinity DataKi:  9.75nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445240(US10669235, Example 31 | US11208381, Example 31)
Affinity DataKi:  10.2nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445240(US10669235, Example 31 | US11208381, Example 31)
Affinity DataKi:  10.2nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507065(US11046672, Example 14)
Affinity DataKi:  10.5nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507083(US11046672, Example 32)
Affinity DataKi:  10.5nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445233(US10669235, Example 24 | US11208381, Example 24)
Affinity DataKi:  10.5nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM445233(US10669235, Example 24 | US11208381, Example 24)
Affinity DataKi:  10.5nMAssay Description:Assay was performed in buffer containing 40 mM Tris pH 7.5, 20 mM MgCl2, 0.1 mg/mL BSA and 1 mM DTT. The inhibitory activities of compounds of the in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM507091(US11046672, Example 40)
Affinity DataKi:  10.6nMAssay Description:The inhibitory activities of compounds of the invention against PDGFRα (PDGFRα Kinase Enzyme System: Promega), were evaluated by mixing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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