Compile Data Set for Download or QSAR
maximum 50k data
Found 361 of affinity data for UniProtKB/TrEMBL: O14939
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50507332(CHEMBL4475943)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50507325(CHEMBL4453586)
Affinity DataIC50:  12nMAssay Description:Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258181(3,4-difluoro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1...)
Affinity DataIC50:  14nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258181(3,4-difluoro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1...)
Affinity DataIC50:  14nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM123746(1-(4-methoxyphenyl)-3-phenyl-1H-pyrazolo[3,4-d]pyr...)
Affinity DataIC50:  15nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)
Affinity DataIC50:  15nMT: 2°CAssay Description:PLD enzymes (50 nM) were reconstituted with phospholipid vesicle substrates. All assays were performed at 37 C with agitation for 30 min. Reactions...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87120(CHEMBL1254577 | N-[2-[1-(3-fluorophenyl)-4-keto-1,...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87120(CHEMBL1254577 | N-[2-[1-(3-fluorophenyl)-4-keto-1,...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50427800(CHEMBL2325485)
Affinity DataIC50:  20nMAssay Description:Inhibition of GFP-tagged PLD2 in human HEK293 cells assessed as deuterated 1-butanol incorporation pretreated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  20nMAssay Description:Cells were seeded into 12-well tissue culture plates to reach 90% confluence at the time of assay. All cell types, aside from the HEK293-gfpPLD2 cell...More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM247409(US9453017, 1)
Affinity DataIC50:  20nMAssay Description:The ability of representative disclosed to block influenza infection was assessed in a cell-based assay using A549 human epithelial cells (ATCC CCL-1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87120(CHEMBL1254577 | N-[2-[1-(3-fluorophenyl)-4-keto-1,...)
Affinity DataIC50:  20nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50206156(CHEMBL246240 | N-(2-(4-(2-oxo-2,3-dihydrobenzo[d]i...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM123744(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  20nMAssay Description:Inhibition of PLD2 (unknown origin)More data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87179(5-fluoranyl-N-[(2R)-1-(4-oxidanylidene-1-phenyl-1,...)
Affinity DataIC50:  23nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87177(5-fluoranyl-N-[2-[1-(3-fluorophenyl)-4-oxidanylide...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87177(5-fluoranyl-N-[2-[1-(3-fluorophenyl)-4-oxidanylide...)
Affinity DataIC50:  25nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50507321(CHEMBL4594070)
Affinity DataIC50:  26nMAssay Description:Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87166(5-fluoranyl-N-[2-[1-(4-fluorophenyl)-4-oxidanylide...)
Affinity DataIC50:  27nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87170(CHEMBL1254176 | N-[2-[1-(4-bromophenyl)-4-keto-1,3...)
Affinity DataIC50:  28nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87151(N-[(1S)-1-[(4-keto-1-phenyl-1,3,8-triazaspiro[4.5]...)
Affinity DataIC50:  29nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87188(CHEMBL471257 | N-[2-(4-keto-1-phenyl-1,3,8-triazas...)
Affinity DataIC50:  30nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87166(5-fluoranyl-N-[2-[1-(4-fluorophenyl)-4-oxidanylide...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87188(CHEMBL471257 | N-[2-(4-keto-1-phenyl-1,3,8-triazas...)
Affinity DataIC50:  30nMAssay Description:Inhibition of GFP-labeled PLD2 in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87158(N-[(1S)-2-[1-(3,4-difluorophenyl)-4-keto-1,3,8-tri...)
Affinity DataIC50:  32nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87159(N-[(1S)-2-[1-(3,4-difluorophenyl)-4-keto-1,3,8-tri...)
Affinity DataIC50:  34nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50427802(CHEMBL2325482)
Affinity DataIC50:  35nMAssay Description:Inhibition of GFP-tagged PLD2 in human HEK293 cells assessed as deuterated 1-butanol incorporation pretreated for 5 mins prior to substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87164(CHEMBL1253820 | N-[2-[1-(4-fluorophenyl)-4-keto-1,...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87164(CHEMBL1253820 | N-[2-[1-(4-fluorophenyl)-4-keto-1,...)
Affinity DataIC50:  40nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258180(4-chloro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1H-be...)
Affinity DataIC50:  42nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50206153(CHEMBL246032 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  42nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258180(4-chloro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1H-be...)
Affinity DataIC50:  42nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50206153(CHEMBL246032 | N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo...)
Affinity DataIC50:  42nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50507326(CHEMBL4436548)
Affinity DataIC50:  43nMAssay Description:Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87142(CHEMBL1254081 | N-[2-[1-(4-chlorophenyl)-4-keto-1,...)
Affinity DataIC50:  50nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87142(CHEMBL1254081 | N-[2-[1-(4-chlorophenyl)-4-keto-1,...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258181(3,4-difluoro-N-(2-(4-(6-fluoro-2-oxo-2,3-dihydro-1...)
Affinity DataIC50:  56nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50326960((S)-N-(1-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspi...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87133(N-[(1S)-2-[1-(3-fluorophenyl)-4-keto-1,3,8-triazas...)
Affinity DataIC50:  60nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50507331(CHEMBL3923136)
Affinity DataIC50:  60nMAssay Description:Inhibition of GFP-fused PLD2 (unknown origin) expressed in HEK293 cells by cellular assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258129(4-chloro-N-(2-(4-(5-fluoro-2-oxo-2,3-dihydro-1H-be...)
Affinity DataIC50:  61nMAssay Description:Inhibition of GFP-labelled human PLD2 HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50258129(4-chloro-N-(2-(4-(5-fluoro-2-oxo-2,3-dihydro-1H-be...)
Affinity DataIC50:  61nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87184(CHEMBL1254653 | N-[2-[1-(3-fluorophenyl)-4-keto-1,...)
Affinity DataIC50:  63nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87184(CHEMBL1254653 | N-[2-[1-(3-fluorophenyl)-4-keto-1,...)
Affinity DataIC50:  63nMAssay Description:Inhibition of human GST-tagged PLD2A in human HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50586324(CHEMBL5085284)
Affinity DataIC50:  64nMAssay Description:Inhibition of PLD2 (unknown origin) expressed in human HEK cells by immunoprecipitationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87192(N-[(1S)-2-[4-(2-keto-3H-benzimidazol-1-yl)piperidi...)
Affinity DataIC50:  66nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87166(5-fluoranyl-N-[2-[1-(4-fluorophenyl)-4-oxidanylide...)
Affinity DataIC50:  66nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM154517(ML299 (5))
Affinity DataIC50:  67nMAssay Description:Inhibition of PLD2 (unknown origin) expressed in human HEK cells by immunoprecipitationMore data for this Ligand-Target Pair
TargetPhospholipase D2(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM87160(CHEMBL1254996 | N-[2-[1-(3,4-difluorophenyl)-4-ket...)
Affinity DataIC50:  69nMAssay Description:Phospholipase D (PLD) generates the lipid second messenger phosphatidic acid as part of a plethora of cellular functions. Phosphatidic acid (PtdOH) i...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
Displayed 1 to 50 (of 361 total ) | Next | Last >>
Jump to: