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Found 374 for UniProtKB: O55242
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312233(US9604926, Compound AZ-66 | US9724435, Compound AZ...)
Affinity DataKi:  0.310nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312168(US9604926, Compound CM-172 | US9724435, Compound C...)
Affinity DataKi:  0.580nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312167(US9604926, Compound CM-171 | US9724435, Compound C...)
Affinity DataKi:  0.940nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002254(2-(1-Benzyl-piperidin-4-yl)-1-(4-fluoro-phenyl)-et...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50374598(CHEMBL272603 | US9604926, Compound CM-156 | US9724...)
Affinity DataKi:  1.28nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312174(US9604926, Compound CM-176 | US9724435, Compound C...)
Affinity DataKi:  1.43nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50017233(CHEMBL592 | LEVO-DROMORAN | LEVORPHANOL)
Affinity DataKi:  1.90nMAssay Description:Binding affinity for mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002232(1-Benzyl-4-(4-phenyl-butoxymethyl)-piperidine; hyd...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002219(1-Benzyl-4-cyclopropoxymethyl-piperidine; compound...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002303(1-Cyclopropylmethyl-4-(3,4-difluoro-phenoxymethyl)...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002207(1-Cyclopropylmethyl-4-(4-fluoro-phenoxymethyl)-pip...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002292(4-[4-(4-Fluoro-benzyloxymethyl)-piperidin-1-ylmeth...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002229(1-Benzyl-4-cyclohexyloxymethyl-piperidine; hydroch...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002190(1-Benzyl-4-(4-fluoro-benzyloxymethyl)-piperidine; ...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002241(1-(4-Chloro-benzyl)-4-(4-fluoro-benzyloxymethyl)-p...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002209(1-(2,2-Dichloro-1-methyl-cyclopropylmethyl)-4-(4-f...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002235(1-Benzyl-4-(4-trifluoromethyl-phenoxymethyl)-piper...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002275(1-Benzyl-4-(3-phenyl-propoxy)-piperidine; compound...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002252(1-Benzyl-4-(4-fluoro-phenoxymethyl)-piperidine; hy...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312234(US9604926, Compound AZ-68 | US9724435, Compound AZ...)
Affinity DataKi:  2.01nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312227(US9604926, Compound SC-6 | US9724435, Compound SC-...)
Affinity DataKi:  2.15nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312154(US9604926, Compound CM-146 | US9724435, Compound C...)
Affinity DataKi:  2.18nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50017232(3-Cyclopropylmethyl-5-ethyl-8-hydroxy-11-methyl-3,...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity for mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312178(US9604926, Compound CM-181 | US9724435, Compound C...)
Affinity DataKi:  2.36nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312161(US9604926, Compound CM-165 | US9724435, Compound C...)
Affinity DataKi:  2.40nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312203(US9604926, Compound CM-401 | US9724435, Compound C...)
Affinity DataKi:  2.89nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM15581(CHEMBL8706 | CLG | CLORGILINE | Clorgyline | N-[3-...)
Affinity DataKi:  2.90nMAssay Description:Inhibition of radioligand binding to sigma1 receptor in C57BL/6 mouse brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002263(1-Cyclohexylmethyl-4-(4-fluoro-benzyloxymethyl)-pi...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002272(1-(2-Cyclopropyl-ethyl)-4-(4-fluoro-phenoxymethyl)...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002217(2-[1-(4-Fluoro-benzyl)-piperidin-4-yl]-1-(4-fluoro...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002280(1-(1-Benzyl-piperidin-4-yl)-2-(4-fluoro-phenyl)-et...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002284(1-Benzyl-4-(4-methoxy-phenoxymethyl)-piperidine | ...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002197(1-(1-Benzyl-piperidin-4-yl)-3-(4-fluoro-phenyl)-pr...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002187(1-(1-Benzyl-piperidin-4-yl)-2-(4-fluoro-phenyl)-et...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002250(1-(4-Fluoro-phenyl)-2-[1-(4-trifluoromethyl-benzyl...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312162(US9604926, Compound CM-166 | US9724435, Compound C...)
Affinity DataKi:  3.15nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002268(1-Benzyl-4-(3-phenyl-propoxymethyl)-piperidine; co...)
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50353845(CHEMBL1830149 | US9604926, Compound CM-341 | US972...)
Affinity DataKi:  3.28nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312147(US9604926, Compound SN-72 | US9724435, Compound SN...)
Affinity DataKi:  3.33nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50374601(CHEMBL408003 | US9604926, Compound CM-135 | US9724...)
Affinity DataKi:  3.37nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002267(1-Benzyl-4-(4-methoxy-benzyloxymethyl)-piperidine;...)
Affinity DataKi:  3.5nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002293(4-(4-Chloro-phenoxymethyl)-1-cyclopropylmethyl-pip...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002290(1-Benzyl-4-[2-(4-fluoro-phenoxy)-ethyl]-piperidine...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002256(4-(4-Fluoro-benzyloxymethyl)-1-naphthalen-2-ylmeth...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002189(2-(1-Benzyl-piperidin-4-yl)-1-(4-methoxy-phenyl)-e...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002222(1-Benzyl-4-benzyloxymethyl-piperidine; hydrochlori...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002194(4-(4-Fluoro-benzyloxymethyl)-1-phenethyl-piperidin...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50002260(1-Cyclopropylmethyl-4-(2,4-dichloro-phenoxymethyl)...)
Affinity DataKi:  4nMAssay Description:In vitro binding affinity for the mouse sigma opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM312169(US9604926, Compound CM-174 | US9724435, Compound C...)
Affinity DataKi:  4.04nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSigma non-opioid intracellular receptor 1(Mus musculus (Mouse))
The University Of Mississippi

US Patent
LigandPNGBDBM50353844(CHEMBL270341 | US9604926, Compound CM-145 | US9724...)
Affinity DataKi:  4.17nMAssay Description:Compounds were evaluated for σ-1 and σ-2 binding in rat brain homogenates. Twelve concentrations of each test ligand (0.001-1,000 nM) were ...More data for this Ligand-Target Pair
In DepthDetails US Patent
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