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Found 48 hits affinity hit(s) for enzyme = Papain with UniProtKB: P00784
Target (A)	Ligand (B)	A in PDB	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C	Explore
Papain Carica papaya	dipeptidyl aldehyde, 52 (tert-butyl N-[(1S)-1-[(2-oxoethyl)carbamoyl]-2-phe...)	19	15.00	-44.65	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	phenylalanine derivative, 44 ((2S)-N-(cyanomethyl)-3-phenyl-2-[(4-phenylphenyl)f...)	19	16.00	-44.49	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 35 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(4...)	19	16.00	-44.49	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 34 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(n...)	19	21.00	-43.82	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 28 (tert-butyl N-[(1S)-2-(4-bromophenyl)-1-[(cyanometh...)	19	29.00	-43.02	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	phenylalanine derivative, 43 ((2S)-N-(cyanomethyl)-3-phenyl-2-(phenylformamido)p...)	19	62.00	-41.13	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 19 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(t...)	19	190.0	-38.36	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 23 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(4...)	19	190.0	-38.36	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 16 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-ph...)	19	260.0	-37.58	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 24 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(4...)	19	270.0	-37.49	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 29 (tert-butyl N-[(1S)-2-(3-bromophenyl)-1-[(cyanometh...)	19	330.0	-36.99	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 17 (benzyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-phenyl...)	19	360.0	-36.77	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	phenylalanine derivative, 42 ((2S)-N-(cyanomethyl)-2-acetamido-3-phenylpropanami...)	19	380.0	-36.64	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 26 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(2...)	19	400.0	-36.51	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 30 (tert-butyl N-[(1S)-2-(2-bromophenyl)-1-[(cyanometh...)	19	460.0	-36.17	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 25 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(3...)	19	500.0	-35.96	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 20 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(t...)	19	570.0	-35.64	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 12 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-3-(m...)	19	650.0	-35.31	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 6 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]butyl...)	19	750.0	-34.95	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 18 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(f...)	19	1200	-33.79	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 39 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(3...)	19	1200	-33.79	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 13 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]penty...)	19	1570	-33.12	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 7 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-3-me...)	19	2000	-32.52	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 5 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-me...)	19	2000	-32.52	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 11 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-cy...)	19	2200	-32.29	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptidyl nitrile, 1 (Cbz-Leu-NH-CH2-CN \| JMC487688 Compound 8 \| benzyl ...)	19	3100	-31.44	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 4 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]propy...)	19	5400	-30.06	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 32 (tert-butyl N-[(1S)-2-(1-benzothiophen-3-yl)-1-[(cy...)	19	7400	-29.28	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 31 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(1...)	19	7600	-29.21	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 38 (N-(cyanomethyl)-2-(naphthalene-2-sulfonamido)aceta...)	19	10000	-28.53	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 22 (tert-butyl N-[(1S)-2-(benzyloxy)-1-[(cyanomethyl)c...)	19	11000	-28.30	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 21 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-3-ph...)	19	12000	-28.08	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 10 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-cy...)	19	13000	-27.88	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 27 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(2...)	19	14000	-27.70	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 3 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]ethyl...)	19	22000	-26.58	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 9 (tert-butyl N-[(1S,2R)-1-[(cyanomethyl)carbamoyl]-2...)	19	26000	-26.17	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 33 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(n...)	19	28000	-25.98	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	phenylalanine derivative, 36 (tert-butyl N-[(1R)-1-[(cyanomethyl)carbamoyl]-2-ph...)	19	41000	-25.04	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 15 (tert-butyl N-[(S)-[(cyanomethyl)carbamoyl](phenyl)...)	19	83000	-23.29	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	phenylalanine derivative, 37 (tert-butyl N-[(1S)-1-[(cyanomethyl)(methyl)carbamo...)	19	>100000	>-22.83	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	methyl ketone, 53 (tert-butyl N-[(1S)-1-[(2-oxopropyl)carbamoyl]-2-ph...)	19	187000	-21.27	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 40 (tert-butyl N-[(1S)-1-[(cyanomethyl)carbamoyl]-2-(2...)	19	299000	-20.11	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	phenylalanine derived propargyl, 54 (tert-butyl N-[(1S)-2-phenyl-1-(prop-2-yn-1-ylcarba...)	19	497000	-18.85	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	phenylalanine derived allylamide, 55 (tert-butyl N-[(1S)-2-phenyl-1-(prop-2-en-1-ylcarba...)	19	497000	-18.85	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 14 (tert-butyl (2S)-2-[(cyanomethyl)carbamoyl]pyrrolid...)	19	537000	-18.66	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	phenylalanine derivative, 48 (2-({N-benzyl-N'-[(tert-butoxy)carbonyl]hydrazineca...)	19	725000	-17.92	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 2 (benzyl N-{[(cyanomethyl)carbamoyl]methyl}carbamate)	19	1599000	-15.96	n/a	n/a	n/a	6.5	25	more..
Papain Carica papaya	dipeptide-derived nitrile, 1 (tert-butyl N-{[(cyanomethyl)carbamoyl]methyl}carba...)	19	>3000000	>-14.40	n/a	n/a	n/a	6.5	25	more..

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