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Report error Found 531 of affinity data for UniProtKB/TrEMBL: P07195
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597915BDBM50597915(CHEMBL5185237)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597915BDBM50597915(CHEMBL5185237)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597916BDBM50597916(CHEMBL5201115)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597916BDBM50597916(CHEMBL5201115)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597908BDBM50597908(CHEMBL5181496)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597908BDBM50597908(CHEMBL5181496)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 197160BDBM197160(GNE-140 (6))
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 197160BDBM197160(GNE-140 (6))
Affinity DataIC50: 5nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50547002BDBM50547002(CHEMBL4753379 | US11247971, Cmpd ID 449 | US117521...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human LDHBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250655BDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597909BDBM50597909(CHEMBL5196929)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597909BDBM50597909(CHEMBL5196929)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50652792BDBM50652792(CHEMBL3752910)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to human LDHB incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597898BDBM50597898(CHEMBL5172378)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597898BDBM50597898(CHEMBL5172378)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597913BDBM50597913(CHEMBL5194549)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597913BDBM50597913(CHEMBL5194549)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597906BDBM50597906(CHEMBL5183539)
Affinity DataIC50: 9.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597896BDBM50597896(CHEMBL5181996)
Affinity DataIC50: 15nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597896BDBM50597896(CHEMBL5181996)
Affinity DataIC50: 15nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597905BDBM50597905(CHEMBL5182266)
Affinity DataIC50: 17nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597905BDBM50597905(CHEMBL5182266)
Affinity DataIC50: 17nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250677BDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250653BDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597914BDBM50597914(CHEMBL5188480)
Affinity DataIC50: 25nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597914BDBM50597914(CHEMBL5188480)
Affinity DataIC50: 25nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250656BDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)
Affinity DataIC50: 27nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534334BDBM50534334(CHEMBL4436150)
Affinity DataIC50: 30nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597910BDBM50597910(CHEMBL5202219)
Affinity DataIC50: 34nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597910BDBM50597910(CHEMBL5202219)
Affinity DataIC50: 34nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534309BDBM50534309(CHEMBL4467769)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534318BDBM50534318(CHEMBL4576717)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103568BDBM50103568(CHEMBL3335794)
Affinity DataIC50: 43nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50616100BDBM50616100(CHEMBL5416627)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human LDHBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597907BDBM50597907(CHEMBL5189879)
Affinity DataIC50: 46nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534335BDBM50534335(CHEMBL4536094)
Affinity DataIC50: 46nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597902BDBM50597902(CHEMBL5177632)
Affinity DataIC50: 47nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250648BDBM50250648(CHEMBL4080497 | US10961200, Compound 20 | US112479...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534330BDBM50534330(CHEMBL4520899)
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534323BDBM50534323(CHEMBL4444963)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066974BDBM50066974(CHEMBL126519 | LDHA Inhibitor, 3 | 7-Benzyl-2,3-di...)
Affinity DataKi:  50nMAssay Description:inhibitory activity against Human Lactate Dehydrogenase (LDH-M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534316BDBM50534316(CHEMBL4453059)
Affinity DataIC50: 55nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534329BDBM50534329(CHEMBL4521960)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597912BDBM50597912(CHEMBL5196259)
Affinity DataIC50: 57nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597912BDBM50597912(CHEMBL5196259)
Affinity DataIC50: 57nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534331BDBM50534331(CHEMBL4475593)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50250652BDBM50250652(CHEMBL4101800 | US10961200, Compound 42 | US112479...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2019
Entry Details Article
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597904BDBM50597904(CHEMBL5176448)
Affinity DataIC50: 65nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597904BDBM50597904(CHEMBL5176448)
Affinity DataIC50: 65nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetL-lactate dehydrogenase B chain(Human)
Genentech

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50534307BDBM50534307(CHEMBL4543949)
Affinity DataIC50: 70nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/28/2021
Entry Details Article
PubMed
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