BindingDB PrimarySearch_ki

Found 476 of affinity data for UniProtKB/TrEMBL: P07861

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50175518((3R,7S)-7-((R)-2-Mercapto-3-phenyl-propionylamino)...)

Ki: 0.0700nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50044866(7-(2-Mercapto-3-phenyl-propionylamino)-6-oxo-1,2,3...)

Ki: 0.0800nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50044866(7-(2-Mercapto-3-phenyl-propionylamino)-6-oxo-1,2,3...)

Ki: 0.0800nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287694(3-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalen...)

Ki: 0.200nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287702((S)-2-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphth...)

Ki: 0.300nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50289194((S)-2-[(S)-4-((R)-2-Mercapto-3-phenyl-propionylami...)

Ki: 0.400nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287689(CHEMBL304233 | [(2-Mercaptomethyl-1,2,3,4-tetrahyd...)

Ki: 0.400nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287700((S)-3-(4-Hydroxy-phenyl)-2-[(2-mercaptomethyl-1,2,...)

Ki: 0.5nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287699(4-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalen...)

Ki: 0.600nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287690(7-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalen...)

Ki: 0.600nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50024096(((R)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)

Ki: 1.60nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL KEGG PC cid PC sid Patents Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50105264(2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-pro...)

Ki: 1.70nMAssay Description:50% inhibitory activity against enkephalinase purified from rat kidney with [3H]D-Ala2-Leu-enkephalin (20 nM) as substrate.More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

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Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50405292(CHEMBL2079630)

Ki: 1.80nMAssay Description:50% inhibitory activity against enkephalinase purified from rat kidney with [3H]D-Ala2-Leu-enkephalin (20 nM) as substrate.More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50024102(((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)

Ki: 1.90nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PDB

3D Structure (crystal)

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50024096(((R)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)

Ki: 2nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL KEGG PC cid PC sid Patents Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287696((S)-2-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphth...)

Ki: 2nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287695((S)-2-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphth...)

Ki: 4nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)

Ki: 4nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of rat kidneyMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287701((4S,7S)-7-(2-Mercapto-acetylamino)-6-oxo-1,2,3,4,6...)

Ki: 5nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50044869(7-(2-Mercapto-acetylamino)-6-oxo-1,2,3,4,6,7,8,12b...)

Ki: 5nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50084628(2-(2-Benzo[1,3]dioxol-5-ylmethyl-3-carboxysulfanyl...)

Ki: 5.60nMAssay Description:Inhibitory activity against neutral EndopeptidaseChecked by AuthorMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287693((S)-2-[(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphth...)

Ki: 7nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287692(CHEMBL431957 | [(2-Mercaptomethyl-indane-2-carbony...)

Ki: 10nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287691(2-Mercaptomethyl-1,2,3,4-tetrahydro-naphthalene-2-...)

Ki: 14nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50283607(7-(2-Mercaptomethyl-3-phenyl-propionylamino)-hepta...)

Ki: 26nMAssay Description:In vitro inhibition against neutral endopeptidase 24.11 (NEP) in rat kidney cortex membraneMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Patents Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50047222(2-[2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-...)

Ki: 31nMAssay Description:Inhibitory activity against endopeptidase 24.15More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50047222(2-[2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-...)

Ki: 40nMAssay Description:Inhibitory activity against endopeptidase 24.11More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM21641(2-(2-benzyl-3-sulfanylpropanamido)acetic acid | CH...)

Ki: 40nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of rat kidneyMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL KEGG PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287698((4S,7R)-7-Mercaptomethyl-6-oxo-1,2,3,4,6,7,8,12b-o...)

Ki: 45nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50044867(7-Mercaptomethyl-6-oxo-1,2,3,4,6,7,8,12b-octahydro...)

Ki: 45nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50047222(2-[2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-...)

Ki: 58nMAssay Description:Inhibitory activity against endopeptidase 24.16More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50021031(CHEMBL19352 | N-[[[(Tyrosylglycyl)amino]methyl]hyd...)

Ki: 110nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of humanMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50021032(CHEMBL281394 | N-[[(Acetylamino)methyl]hydroxyphos...)

Ki: 140nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of rat kidneyMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50021033(CHEMBL429227 | N-[[[(Tyrosyl-D-alanyl)amino]methyl...)

Ki: 280nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of humanMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50287697((4S,7S)-7-Mercaptomethyl-6-oxo-1,2,3,4,6,7,8,12b-o...)

Ki: >300nMAssay Description:Inhibition of neutral endopeptidase(NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50044867(7-Mercaptomethyl-6-oxo-1,2,3,4,6,7,8,12b-octahydro...)

Ki: >300nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50281462((R)-2-[(6S,7S)-6-((R)-2-Mercapto-3-phenyl-propiony...)

Ki: 330nMAssay Description:Compound was tested for inhibition of neutral endopeptidase (NEP).More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL KEGG PC cid PC sid

Details Article

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50021030(CHEMBL277431 | N-(Hydroxymethylphosphinothioyl)phe...)

Ki: 420nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of humanMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50021026(CHEMBL417094 | N-[[(Acetylamino)methyl]hydroxyphos...)

Ki: 850nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of rat kidneyMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50047223(2-[2-(2-Benzyl-3-hydroxycarbamoyl-propionylamino)-...)

Ki: 1.32E+3nMAssay Description:Inhibitory activity against endopeptidase 24.16More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50044868(7-(1-Carboxy-3-phenyl-propylamino)-6-oxo-1,2,3,4,6...)

Ki: >1.00E+4nMAssay Description:Binding affinity of compound against rat kidney neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50021029(CHEMBL19443 | N-[[(Benzoylamino)methyl]hydroxyphos...)

Ki: 1.06E+4nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of rat kidneyMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50021034(CHEMBL20089 | N-[[(Phenylacetyl)amino]methyl]hydro...)

Ki: 8.02E+4nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of rat kidneyMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50367255(CHEMBL1744144)

Ki: 1.60E+5nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of rat kidneyMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50021027(CHEMBL277394 | N-[[[(3-Phenylpropionoyl)amino]meth...)

Ki: 1.21E+6nMAssay Description:Binding affinity towards enkephalinase (metalloendopeptidase, E.C.3.4.24.11) of rat kidneyMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50008612(CHEMBL154588 | Sodium; 3-(2-mercaptomethyl-3-pheny...)

IC50: 0.270nMAssay Description:In vitro inhibitory activity against enkephalinase enzyme from rat.More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50024094((R,S) 2-(2-Mercaptomethyl-3-phenyl-propionylamino)...)

IC50: 0.410nMAssay Description:Concentration for 50% inhibition of activity of rat kidney enkephalinaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50024101((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)

IC50: 0.480nMAssay Description:Concentration for 50% inhibition of activity of rat kidney enkephalinaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50024100((R,S) N-(1-Mercaptomethyl-2-phenyl-ethyl)-2-methyl...)

IC50: 0.540nMAssay Description:Concentration for 50% inhibition of activity of rat kidney enkephalinaseMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Neprilysin(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL

PNG

BDBM50251742((3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro...)

IC50: 0.600nMAssay Description:Inhibition of enkephalinase activity in synaptic membranes prepared from rat striatumMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar

Purchase CHEMBL KEGG MMDB PC cid PC sid PDB Patents Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)

Displayed 1 to 50 (of 476 total ) | Next | Last >>

Filter my 476 hits

Targets 1▿
- Neprilysin 476
Publications 38▿
- J Med Chem 38: 1689-700 (1995) 43
- J Med Chem 35: 602-8 (1992) 37
- J Med Chem 43: 488-504 (2000) 32
- Bioorg Med Chem Lett 5: 145-150 (1995) 26
- J Med Chem 32: 2519-26 (1989) 25
- J Med Chem 38: 5023-30 (1996) 23
- Bioorg Med Chem Lett 4: 1783-1788 (1994) 23
- J Med Chem 37: 498-511 (1994) 22
- Bioorg Med Chem Lett 6: 65-70 (1996) 21
- J Med Chem 39: 494-502 (1996) 19
- J Med Chem 28: 1158-69 (1985) 19
- Bioorg Med Chem Lett 6: 2053-2058 (1996) 16
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Institutions 15▿
- TBA 185
- Ciba-Geigy 130
- Dainippon Pharmaceutical 37
- Novartis Institute For Biomedical Research 32
- Bristol-Myers Squibb Pharmaceutical Research Institute 31
- R & D, Zambon Group 14
- The Bristol-Myers Squibb Pharmaceutical Research Institute 8
- Marion Merrell Dow Research Institute 7
- F. Hoffmann-La Roche 6
- University Of Queensland 6
- Shionogi 6
- Institute Of Biomedical Chemistry Of Russian Academy Of Medical Sciences 5
- Ccipe-Faculté 4
- Pfizer 3
- University Of Bath 2
Affinity: 0.070 to 2.0E+6 nM▿
- Ki 45
- IC50 431
- Affinity ≤ nM
Xtal structures: 6
Docked structures: 0
Catalog Cmpds: 22