Affinity DataIC50: 0.400nMAssay Description:Inhibition of DNA polymerase alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: <1nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair
Affinity DataEC50: <1nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: <1nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: <1nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: <1nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: <1nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: <1nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Compound was evaluated for 50% inhibition of DHBV DNA polymerase (duck hepatitis B virus)More data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Compound was evaluated for 50% inhibition of DHBV DNA polymerase (duck hepatitis B virus)More data for this Ligand-Target Pair
Affinity DataIC50: 680nMAssay Description:Inhibition of DNA polymerase alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 830nMAssay Description:Inhibition of DNA polymerase alpha from human KB3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for 50% inhibition of DHBV DNA polymerase (duck hepatitis B virus)More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Compound was evaluated for 50% inhibition of DHBV DNA polymerase (duck hepatitis B virus)More data for this Ligand-Target Pair
Affinity DataKi: 1.00E+3nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataKi: 1.18E+3nMAssay Description:Binding affinity to DNA polymerase alpha (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.40E+3nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human DNA polymerase alpha using 5' end radiolabeled 24nt DNA/48nt DNA as primer/template after 5 mins by PAGE analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human DNA polymerase alpha by microplate reader analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMpH: 7.5Assay Description:Inhibition of human alpha DNA polymerase (95 uL) activity in a solution containg 6.4 mM HEPES (pH 7.5) upon incubation for 12 minutes at 26 degrees C...More data for this Ligand-Target Pair
Affinity DataKi: 2.60E+3nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Compound was evaluated for the inhibitory activity against Human alpha polymeraseMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 3.00E+3nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human DNA polymerase-alpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataKi: 3.75E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+3nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human DNA polymerase alpha using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP...More data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human DNA polymerase alpha using 5-end radiolabeled 24nt to 48nt DNA as primer template after 5 mins in presence of dCTP/dGTP/dTTP/dATP...More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant DNA polymerase alpha expressed in baculovirus infected SF9 cells after 12 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant DNA polymerase alpha expressed in baculovirus infected SF9 cells after 12 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 5.00E+3nMAssay Description:Compound was evaluated for the concentration which gives half-maximal inhibition of Chinese Hamster Ovary DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataEC50: 7.00E+3nMAssay Description:Effective concentration against DNA polymerase alphaMore data for this Ligand-Target Pair
Affinity DataKi: 7.50E+3nMAssay Description:Compound was tested for its inhibitory activity against HeLa DNA polymerase alpha, Ki values were obtained in the absence of dGTPMore data for this Ligand-Target Pair
Affinity DataKi: 7.84E+3nMAssay Description:Inhibition constant against DNA polymerase alpha non competitively on dNTP substrateMore data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of DNA polymerase alphaMore data for this Ligand-Target Pair





















3D Structure (crystal)




















