Compile Data Set for Download or QSAR
Report error Found 330 of affinity data for UniProtKB/TrEMBL: P09936
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699777(US20240335427, Compound 8)
Affinity DataIC50: 12nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50645685(CHEMBL5589657)
Affinity DataIC50: 50nMAssay Description:Inhibition of 6His-tagged human UCHL1 using Ub-Rh110Gly as fluorogenic substrate preincubated for 1 hr followed by substrate addition by plate reader...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50590283(CHEMBL5169766 | US20230303547, Reference Example D...)
Affinity DataIC50: 73nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699808(US20240335427, Compound 38)
Affinity DataIC50: 89nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699789(US20240335427, Compound 19)
Affinity DataIC50: 90nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445149(US10669234, Example 95 | (2S,4S)-4-Fluoro-2-(4-(5-...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445088(US10669234, Example 27 | (S)-2-(4-(1H-pyrrolo [2,3...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445088(US10669234, Example 27 | (S)-2-(4-(1H-pyrrolo [2,3...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM552974((2S,4S)-4-fluoro-2-(4-(5- | US11319287, Example 29)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445158(US10669234, Example 115 | (S)-2-(5-(3-(trifluoro- ...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445080(US10669234, Example 19 | (S)-2-(4-(5-(Trifluoromet...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445160(US10669234, Example 117 | (S)-2-(4-(1H-pyrrolo[2,3...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699796(US20240335427, Compound 26)
Affinity DataIC50: 100nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445158(US10669234, Example 115 | (S)-2-(5-(3-(trifluoro- ...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445160(US10669234, Example 117 | (S)-2-(4-(1H-pyrrolo[2,3...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699782(US20240335427, Compound 12)
Affinity DataIC50: 100nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445080(US10669234, Example 19 | (S)-2-(4-(5-(Trifluoromet...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445090(US10669234, Example 29 | (2S,4S)-4-fluoro-2-(4-(5-...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445149(US10669234, Example 95 | (2S,4S)-4-Fluoro-2-(4-(5-...)
Affinity DataIC50: 100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699802(US20240335427, Compound 32)
Affinity DataIC50: 104nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  106nMAssay Description:Binding affinity to human UCHL1 incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699798(US20240335427, Compound 28)
Affinity DataIC50: 155nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50589875(8RK64)
Affinity DataIC50: 230nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-Rho-Morpholine as substrate preincubated with enzyme for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50594734(CHEMBL5191704)
Affinity DataIC50: 230nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-Rho-morpholine as substrate preincubated for 30 mins followed by substrate addition by fluorescence bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50589875(8RK64)
Affinity DataIC50: 230nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-AMC as substrate preincubated with enzyme for 1 hr followed by substrate addition and measured for 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50514120(CHEMBL3407553)
Affinity DataKi:  400nMAssay Description:Competitive inhibition of UCHL1 in human H1299 cells using Ub-AMC substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM699805(US20240335427, Compound 35)
Affinity DataIC50: 420nMAssay Description:In vitro JOSD1 activity assay was carried out with Ubiquitin-AMC assay. The Ubiquitin-AMC assay was carried out as previously described (Wernig, et a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2025
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445086(US10669234, Example 25 | (S)-2-(4-(3,5-dimethyl- 1...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445151(US10669234, Example 97 | (S)-2-(4-(5-(Trifluoromet...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445150(US10669234, Example 96 | N-(4-(1-(Cyano-L-prolyl)i...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445082(US10669234, Example 21 | (S)-2-(4-(5-Methyl-1H-pyr...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445155(US10669234, Example 109 | (S)-N-(4-(3-Chlorophenyl...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445081(US10669234, Example 20 | (S)-2-(4-(1H-Pyrazol-4-yl...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445159(US10669234, Example 116 | 4-(1-(cyano-L-prolyl)ind...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445163(US10669234, Example 120 | (S)-2-(4-(2- (methylamin...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445165(US10669234, Example 122 | (S)-2-(4-(1H-pyrazolo[3,...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM565105(US11414402, Example 19 | N-(1-cyanopyrrolidin-3-yl...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445135(US10669234, Example 74 | 4-(1-(Cyano-L-prolyl)indo...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445137(US10669234, Example 76 | (S)-2-(4-(2-Aminopyridin-...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445098(US10669234, Example 37 | (S)-2-(4-(3-cyclopropyl-1...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445100(US10669234, Example 39 | (S)-2-(4-(Pyridin-4-yl)in...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445099(US10669234, Example 38 | (S)-2-(4-(2-aminopyrimidi...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445140(US10669234, Example 81 | (S)-1-cyano-N-(4- (6-meth...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445145(US10669234, Example 89 | 1-(Cyano-L-prolyl)-N-meth...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2022
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445089(US10669234, Example 28 | (S)-4,4-difluoro-2-(4-(5-...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445091(US10669234, Example 30 | US11319287, Example 30 | ...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445114(US10669234, Example 53 | (S)-N-(4-(2-chlorophenyl)...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445113(US10669234, Example 52 | (S)-N-(4-(3-chlorophenyl)...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445115(US10669234, Example 54 | (S)-1-cyano-N-methyl-N-(4...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM445108(US10669234, Example 47 | (S)-1-cyano-N-(4-(3- meth...)
Affinity DataIC50: 550nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 (μM) in 50% DMSO in a 96-well p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent

Displayed 1 to 50 (of 330 total ) | Next | Last >>
Jump to: