Compile Data Set for Download or QSAR
Report error Found 487 of affinity data for UniProtKB/TrEMBL: P11413
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50593541(CHEMBL5177201)
Affinity DataIC50: 70nMAssay Description:Inhibition of human G6PDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50652793(CHEMBL5653589)
Affinity DataKd:  107nMAssay Description:Binding affinity to human G6PD incubated for 45 mins by Kinobead based pull down assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50593538(CHEMBL1521758)
Affinity DataIC50: 200nMAssay Description:Inhibition of human C-terminal His tagged G6PD overexpressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50593540(CHEMBL5207151)
Affinity DataIC50: 600nMAssay Description:Inhibition of human C-terminal His tagged G6PD overexpressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50630970(CHEMBL5172312)
Affinity DataEC50:  800nMAssay Description:Activation of G6PD (unknown origin) expressed in Escherichia coli C43(DE3) cells using G6P as substrate in presence of NADP+ by resazurin dye-based a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388478(CHEMBL2057971)
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388488(CHEMBL2057293)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of G6PD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388488(CHEMBL2057293)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKi:  1.19E+3nMAssay Description:Competitive inhibition of G6PD (unknown origin) using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten analys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388490(CHEMBL2057300)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of G6PD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388494(CHEMBL2057640)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of G6PD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388494(CHEMBL2057640)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388490(CHEMBL2057300)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388489(CHEMBL2057296)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388522(CHEMBL2057294)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388492(CHEMBL2057310)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388523(CHEMBL2057974)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKi:  2.54E+3nMAssay Description:Competitive inhibition of G6PD (unknown origin) using varying concentrations of G6P and NADP+ as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50593537(CHEMBL3359046)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human G6PDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50593537(CHEMBL3359046)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human C-terminal His tagged G6PD overexpressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50593536(CHEMBL5197333)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human G6PDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human G6PDH using NADP as substrate by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50593536(CHEMBL5197333)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human C-terminal His tagged G6PD overexpressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50593539(CHEMBL5199703)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human C-terminal His tagged G6PD overexpressed in Escherichia coli BL21More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of human G6PDH using glucose-6-phosphate as substrate by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388491(CHEMBL2057307)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKd:  3.64E+3nMAssay Description:Binding affinity to G6PD (unknown origin) assessed as equilibrium dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388493(CHEMBL2057318)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388495(CHEMBL2057301)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388491(CHEMBL2057307)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388520(CHEMBL2057291)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of G6PD (unknown origin) assessed as reduction in 6-phospho-D-glucono-1,5-lactone and NADPH production using glucose-6-phosphate and NADP+...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388486(CHEMBL2057979)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM94597((Z)-2-butenedioate;10-(1-methyl-4-piperidinylidene...)
Affinity DataKi:  5.20E+3nM IC50: 8.00E+3nMAssay Description:Ketotifen, dacarbazine, thiocolchicoside, meloxicam, methotrexate, furosemide, olanzapine, methylprednizolone acetate, paricalcitol, ritodrine hydroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388477(CHEMBL1908012)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKi:  5.79E+3nMAssay Description:Non-competitive inhibition of G6PD (unknown origin) using glucose-6-phosphate and varying concentrations of NADP+ as substrate by Michaelis-Menten an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50223368(Prasterone | 3beta-hydroxyandrost-5-en-17-one | CH...)
Affinity DataKi:  6.20E+3nMAssay Description:Inhibition of human G6PDH using NADP as substrate by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388484(CHEMBL2057978)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388498(CHEMBL2057297)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388489(CHEMBL2057296)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50273(MLS000697055 | 2-[[1-hydroxy-4-[(2,4,5-trimethylph...)
Affinity DataIC50: 8.73E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2011
Entry Details
PCBioAssay
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM46667(2-phenyl-1,2-benzothiazol-3-one (1) | cid_164981 |...)
Affinity DataIC50: 8.87E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/4/2011
Entry Details
PCBioAssay
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50223368(Prasterone | 3beta-hydroxyandrost-5-en-17-one | CH...)
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of human G6PDH using glucose-6-phosphate as substrate by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388492(CHEMBL2057310)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388479(CHEMBL2057973)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50236240(Epiandrosterone | epi-andosterone | 5alpha-androst...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of G6PD (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388488(CHEMBL2057293)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of G6PD in HEK293T cells assessed as accumulation of 6-phosphogluconate after 5 hrs by LC-MS/MS analysis using 6-aminonicotinamideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50388500(CHEMBL2057299)
Affinity DataIC50: 9.90E+3nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50096619(CHEMBL97453 | 1,8,9-Trihydroxy-3-methoxy-benzo[4,5...)
Affinity DataKi:  9.94E+3nMAssay Description:Non-competitive inhibition of G6PD (unknown origin) using varying concentrations of G6P and NADP+ as substrate by Michaelis-Menten analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
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