Compile Data Set for Download or QSAR
Report error Found 71 of affinity data for UniProtKB/TrEMBL: P16390
LigandChemical structure of BindingDB Monomer ID 50115772BDBM50115772(CHEMBL3609094)
Affinity DataIC50: 0.0230nMAssay Description:Displacement of [125I]-ChTX from mouse Kv1.3 after 20 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50083523BDBM50083523([1-Benzyl-1H-quinolin-(4E)-ylidene]-pentyl-amine |...)
Affinity DataIC50: 230nMAssay Description:Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50098785BDBM50098785(4-Benzhydryloxymethyl-1-[3-(4-methoxy-phenyl)-prop...)
Affinity DataIC50: 280nMAssay Description:Blockade of peak steady-state K+ currents of voltage-gated potassium channel subunit Kv1.3 in mouse fibroblasts L929 at 50 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182585BDBM50182585(5-acetyl-7-(4'-bromo)benzyloxy-6-hydroxy-4-methoxy...)
Affinity DataEC50:  400nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182591BDBM50182591(1-(7-(4-(trifluoromethyl)benzyloxy)-6-hydroxy-4-me...)
Affinity DataEC50:  420nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182638BDBM50182638(1-(7-(4-chlorobenzyloxy)-6-hydroxy-4-methoxybenzof...)
Affinity DataEC50:  420nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182593BDBM50182593(1-(7-(3-(trifluoromethoxy)benzyloxy)-6-hydroxy-4-m...)
Affinity DataEC50:  450nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182587BDBM50182587(5-acetyl-4-(4'-chloro)benzyloxy-6-hydroxy-7-methox...)
Affinity DataEC50:  480nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182603BDBM50182603(1-(4-(4-bromobenzyloxy)-6-hydroxy-7-methoxybenzofu...)
Affinity DataEC50:  500nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182586BDBM50182586(1-(7-(4-benzoylbenzyloxy)-6-hydroxy-4-methoxybenzo...)
Affinity DataEC50:  500nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182600BDBM50182600(1-(4-(4-benzoylbenzyloxy)-6-hydroxy-7-methoxybenzo...)
Affinity DataEC50:  500nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182595BDBM50182595(1-(4-(4-(trifluoromethyl)benzyloxy)-6-hydroxy-7-me...)
Affinity DataEC50:  510nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182599BDBM50182599(1-(4-(3-(trifluoromethoxy)benzyloxy)-6-hydroxy-7-m...)
Affinity DataEC50:  550nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182628BDBM50182628(1-(7-(3-chlorobenzyloxy)-6-hydroxy-4-methoxybenzof...)
Affinity DataEC50:  600nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182607BDBM50182607(1-(7-(3-nitrobenzyloxy)-6-hydroxy-4-methoxybenzofu...)
Affinity DataEC50:  600nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182631BDBM50182631(1-(7-(4-(trifluoromethoxy)benzyloxy)-6-hydroxy-4-m...)
Affinity DataEC50:  600nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182601BDBM50182601(1-(4-(3-methoxybenzyloxy)-6-hydroxy-7-methoxybenzo...)
Affinity DataEC50:  680nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182626BDBM50182626(1-(7-(2-chlorobenzyloxy)-6-hydroxy-4-methoxybenzof...)
Affinity DataEC50:  700nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182629BDBM50182629(1-(4-(4-isopropylbenzyloxy)-6-hydroxy-7-methoxyben...)
Affinity DataEC50:  700nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182588BDBM50182588(1-(7-(4-fluorobenzyloxy)-6-hydroxy-4-methoxybenzof...)
Affinity DataEC50:  700nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182604BDBM50182604(1-(7-(3-fluorobenzyloxy)-6-hydroxy-4-methoxybenzof...)
Affinity DataEC50:  750nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182637BDBM50182637(1,6-bis(5-acetyl-4-ethoxy-7-methoxybenzofuran-6-yl...)
Affinity DataEC50:  800nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182635BDBM50182635(1-[4-(1,1'-biphenyl-4-ylmethoxy)-6-hydroxy-7-metho...)
Affinity DataEC50:  900nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50176999BDBM50176999(CHEMBL3814333)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of mouse Kv1.3 expressed in L929 cells at -80 mV holding potential by whole cell patch-clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182606BDBM50182606(1-(7-(4-isopropylbenzyloxy)-6-hydroxy-4-methoxyben...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182610BDBM50182610(1-{6-hydroxy-7-methoxy-4-[(3-methylbenzyl)oxy]-1-b...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182625BDBM50182625(1-(4-(4-fluorobenzyloxy)-6-hydroxy-7-methoxybenzof...)
Affinity DataEC50:  1.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182592BDBM50182592(1-[7-(Biphenyl-2-ylmethoxy)-6-hydroxy-4-methoxy-be...)
Affinity DataEC50:  1.10E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182589BDBM50182589(1-[7-(Biphenyl-4-ylmethoxy)-6-hydroxy-4-methoxy-be...)
Affinity DataEC50:  1.20E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182605BDBM50182605(1-(4-(2-chlorobenzyloxy)-6-hydroxy-7-methoxybenzof...)
Affinity DataEC50:  1.20E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182608BDBM50182608(1-[6-Hydroxy-4-methoxy-7-(3-methyl-benzyloxy)-benz...)
Affinity DataEC50:  1.20E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182597BDBM50182597(5-acetyl-4,7-benzyloxy-6-hydroxybenzofuran | CHEMB...)
Affinity DataEC50:  1.20E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182609BDBM50182609(1-(4-(3-fluorobenzyloxy)-6-hydroxy-7-methoxybenzof...)
Affinity DataEC50:  1.20E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182613BDBM50182613(5-acetyl-7-benzyloxy-6-hydroxy-4-methoxybenzofuran...)
Affinity DataEC50:  1.20E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182618BDBM50182618(1-(4-(3-chlorobenzyloxy)-6-hydroxy-7-methoxybenzof...)
Affinity DataEC50:  1.40E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182615BDBM50182615(1-(4-(3-nitrobenzyloxy)-6-hydroxy-7-methoxybenzofu...)
Affinity DataEC50:  1.40E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182617BDBM50182617(1-(4-(4-tert-butylbenzyloxy)-6-hydroxy-7-methoxybe...)
Affinity DataEC50:  1.50E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182633BDBM50182633(1-(4-(4-methoxybenzyloxy)-6-hydroxy-7-methoxybenzo...)
Affinity DataEC50:  1.50E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182639BDBM50182639(1-(4-(2-fluorobenzyloxy)-6-hydroxy-7-methoxybenzof...)
Affinity DataEC50:  1.70E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182611BDBM50182611(1-(4-(4-(trifluoromethoxy)benzyloxy)-6-hydroxy-7-m...)
Affinity DataEC50:  1.80E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182598BDBM50182598(1-[6-Hydroxy-4-methoxy-7-(2-methyl-benzyloxy)-benz...)
Affinity DataEC50:  1.90E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182619BDBM50182619(1-{6-hydroxy-7-methoxy-4-[(2-methylbenzyl)oxy]-1-b...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182594BDBM50182594(1-[4-(1,1'-biphenyl-2-ylmethoxy)-6-hydroxy-7-metho...)
Affinity DataEC50:  2.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182640BDBM50182640(1-(7-(2-fluorobenzyloxy)-6-hydroxy-4-methoxybenzof...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182630BDBM50182630(1-(4-(benzyloxy)-6-hydroxy-7-methoxybenzofuran-5-y...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182616BDBM50182616(3-(4-ethoxy-6-hydroxy-7-methoxybenzofuran-5-yl)-1-...)
Affinity DataEC50:  2.50E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182627BDBM50182627(1-(6-hydroxy-4-methoxy-7-phenoxybenzofuran-5-yl)et...)
Affinity DataEC50:  3.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182612BDBM50182612(1-(6-hydroxy-7-methoxy-4-phenoxybenzofuran-5-yl)et...)
Affinity DataEC50:  4.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182620BDBM50182620(1-(6-hydroxy-7-methoxy-4-propoxybenzofuran-5-yl)et...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50182634BDBM50182634(1-(6-hydroxy-7-methoxy-4-(naphthalen-2-ylmethoxy)b...)
Affinity DataEC50:  5.00E+3nMAssay Description:Effect on blockade of mouse Kv1.3 channel expressed in L929 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
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