Affinity DataKd: 0.300nMAssay Description:The affinity of Example 1-14 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
Affinity DataKd: 0.400nMAssay Description:The affinity of Example 1-14 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
Affinity DataKd: <1nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:The affinity of Example 1-14 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
Affinity DataKd: <1nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-...More data for this Ligand-Target Pair
Affinity DataKd: <1nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
Affinity DataKd: 1nMAssay Description:Binding affinity to human galectin-3 assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-...More data for this Ligand-Target Pair
Affinity DataKd: 1.60nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:Binding affinity to human galectin 3 C-terminal domain expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analy...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:The assay was adapted to be able to measure the high affinity of compounds for galectin-3 by using the below probe constructed to have high affinity ...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
Affinity DataKd: 2nMAssay Description:The affinity of Example 1-106 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the int...More data for this Ligand-Target Pair
Affinity DataKd: 2.20nMAssay Description:Binding affinity at recombinant human Galectin-3 assessed as dissociation constant by fluorescence anisotropy assayMore data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-...More data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-...More data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Binding affinity to galectin-3 (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Affinity DataKd: 2.30nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-...More data for this Ligand-Target Pair
Affinity DataKd: 2.70nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-...More data for this Ligand-Target Pair
Affinity DataKd: 2.90nMAssay Description:Binding affinity to human galectin 3 C-terminal domain expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analy...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:Binding affinity to human galectin-3 assessed as dissociation constant by competitive fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:The affinity of compounds 3a-c for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the in...More data for this Ligand-Target Pair
Affinity DataKd: 3nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
Affinity DataKd: 3.20nMAssay Description:Binding affinity to human galectin 3 C-terminal domain expressed in Escherichia coli BL21(DE3) by competitive isothermal titration calorimetric analy...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-(3,5-dimethoxybenzamido)-1,1'-sulfanediyl-di-beta-...More data for this Ligand-Target Pair
Affinity DataKd: 4nMAssay Description:Displacement of 3,3'-dideoxy-3-[4-(fluorescein-5-yl-carbonylaminomethyl)-1H-1,2,3-triazol-1-yl]-3'-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of biotin-asialofetuin binding to human Gal3 measured after 90 mins by HTRF competition assayMore data for this Ligand-Target Pair
Affinity DataKd: 5nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:The affinity of Example 1-14 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
Affinity DataKd: 6nMAssay Description:The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of his-tagged N-terminal recombinant human Gal-3 preincubated for 30 mins followed by Biotin-ASF addition and measured after 1 hr by HTRF ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.90nMAssay Description:Inhibition of His-tagged recombinant human Gal-3 preincubated for 30 mins followed by B-ASF addition measured after 1 hr by time resolved fluorescenc...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The Gal-3 assays were performed in 384 white Opti plates in three replicates at room temperature with gentle shaking at 250-300 rpmFrom the original ...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of his-tagged N-terminal recombinant human Gal-3 preincubated for 30 mins followed by Biotin-ASF addition and measured after 1 hr by HTRF ...More data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:The affinity of Example 1-5 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inter...More data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:The affinity of compounds S8a-c, S11, S16, S20a-b and S21 for galectins were determined by a fluorescence anisotropy assay where the compound was use...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Affinity DataKd: 7nMAssay Description:The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human Galectin-3More data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 8nMAssay Description:The inhibitory activity of compounds is determined in competitive binding assays. This spectrophotometric assay measures the binding of biotinylated ...More data for this Ligand-Target Pair
Affinity DataKd: 8nMAssay Description:The affinity of Example 1-71 for galectins were determined by a fluorescence anisotropy assay where the compound was used as an inhibitor of the inte...More data for this Ligand-Target Pair
