TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 27nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 282nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 216nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 253nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 25nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 3.49E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 4.06E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 4.48E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 94nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 57nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 1.82E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 257nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 1.14E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 1.16E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 8.76E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 6.36E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 3.49E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 6.64E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 2.20E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 4.21E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 1.14E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 1.43E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 3.52E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 7.03E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 749nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 0.420nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 4.00E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 0.230nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing tBid assessed as reduction in apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 164nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 364nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 817nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 69nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 66nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 1.59E+3nMAssay Description:Inhibition of SDHB in human U2OS cells over-expressing Bim assessed as inhibition of apoptosis preincubated for 1 hr followed by doxycyclin addition ...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair
TargetSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial(Homo sapiens (Human))
Peking University
Curated by ChEMBL
Peking University
Curated by ChEMBL
Affinity DataEC50: 500nMAssay Description:In order to identify the target protein of tTC09 apoptosis inhibitors, we synthesized two sets of probes for target identification based on the SAR s...More data for this Ligand-Target Pair