Compile Data Set for Download or QSAR
Report error Found 187 for UniProtKB: P27732
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029417BDBM50029417([4-(4-Methoxy-phenyl)-4H-benzo[b]pyrrolo[1,2-d][1,...)
Affinity DataIC50: 0.430nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422202BDBM50422202(CHEMBL24662)
Affinity DataIC50: 0.780nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336640BDBM50336640((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50018796BDBM50018796(CHEMBL25676 | 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-...)
Affinity DataKi:  1.20nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50018796BDBM50018796(CHEMBL25676 | 2,6-Dimethyl-4-(3-nitro-phenyl)-1,4-...)
Affinity DataIC50: 2.60nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50336640BDBM50336640((nifedipine) 2,6-Dimethyl-4-(2-nitro-phenyl)-1,4-d...)
Affinity DataIC50: 2.70nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422200BDBM50422200(CHEMBL278804)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422196BDBM50422196(CHEMBL25512)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50453799BDBM50453799(Niguldipine)
Affinity DataKi:  4.60nMAssay Description:Binding affinity for rat L-type [Ca2+] channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072809BDBM50072809(4-[2-(4-Cyano-furazan-3-ylmethoxy)-phenyl]-2,6-dim...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317813BDBM50317813(3-ethyl 5-(2-(methacryloyloxy)ethyl)2,6-dimethyl-4...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317802BDBM50317802(3-allyl 5-methyl 2,6-dimethyl-4-(2-nitrophenyl)-1,...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317817BDBM50317817(3-cyclohex-2-enyl 5-methyl 2,6-dimethyl-4-(3-nitro...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072809BDBM50072809(4-[2-(4-Cyano-furazan-3-ylmethoxy)-phenyl]-2,6-dim...)
Affinity DataIC50: 10nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317840BDBM50317840(diethyl 4-(2,3-difluorophenyl)-2,6-dimethyl-1,4-di...)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317833BDBM50317833(3-methyl 5-(3-phenylbutyl)2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317836BDBM50317836(3-methyl 5-(3-phenoxypropyl)2,6-dimethyl-4-(3-nitr...)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422191BDBM50422191(CHEMBL24998)
Affinity DataIC50: 12nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317835BDBM50317835(3-(2-(benzyloxy)ethyl)5-methyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317815BDBM50317815(3-benzyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50280077BDBM50280077(sec-Butyl-[4-(2,4-dimethoxy-phenyl)-4H-benzo[b]pyr...)
Affinity DataIC50: 15nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317775BDBM50317775(diethyl 2,6-dimethyl-4-(2-(methylthio)phenyl)-1,4-...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317804BDBM50317804(3-allyl 5-ethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317803BDBM50317803(3-allyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317826BDBM50317826(3-furan-2-ylmethyl 5-methyl 2,6-dimethyl-4-(3-nitr...)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072811BDBM50072811(2,6-Dimethyl-4-[2-(4-methyl-5-oxy-furazan-3-ylmeth...)
Affinity DataKi:  18nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317788BDBM50317788(diethyl 2-butyl-6-methyl-4-(3-nitrophenyl)-1,4-dih...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317821BDBM50317821(3-(3,4-difluorobenzyl)5-methyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317807BDBM50317807(3-cyclopropylmethyl 5-methyl 2,6-dimethyl-4-(3-nit...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072818BDBM50072818(4-[2-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...)
Affinity DataKi:  21nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317810BDBM50317810(3-methyl 5-(2,2,2-trifluoroethyl)2,6-dimethyl-4-(3...)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422192BDBM50422192(CHEMBL25278)
Affinity DataIC50: 22nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317825BDBM50317825(3-benzo[d][1,3]dioxol-5-ylmethyl 5-methyl 2,6-dime...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317809BDBM50317809(3-(2-chloroethyl)5-methyl 2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317827BDBM50317827(3-methyl 5-thiophen-2-ylmethyl 2,6-dimethyl-4-(3-n...)
Affinity DataIC50: 23nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072803BDBM50072803(2,6-Dimethyl-4-[2-(4-methyl-furazan-3-ylmethoxy)-p...)
Affinity DataKi:  27nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072818BDBM50072818(4-[2-(4-Cyano-5-oxy-furazan-3-ylmethoxy)-phenyl]-2...)
Affinity DataIC50: 27nMAssay Description:Inhibitory concentration for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317820BDBM50317820(3-(3-fluorobenzyl)5-methyl 2,6-dimethyl-4-(3-nitro...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50422203BDBM50422203(CHEMBL284195)
Affinity DataIC50: 29nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072814BDBM50072814(4-[2-(4-Cyano-2-oxy-furazan-3-ylmethoxy)-phenyl]-2...)
Affinity DataKi:  30nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50029414BDBM50029414(Acetic acid 4-(4-methoxy-phenyl)-4H-benzo[b]pyrrol...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]nitrendipine binding to L-type [Ca2+] channel in rat cortex homogenate, activity expressed as pIC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072810BDBM50072810(2,6-Dimethyl-4-[2-(4-methyl-2-oxy-furazan-3-ylmeth...)
Affinity DataKi:  32nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317822BDBM50317822(3-methyl 5-(2,4,6-trichlorobenzyl)2,6-dimethyl-4-(...)
Affinity DataIC50: 34nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317805BDBM50317805(3-but-3-ynyl 5-methyl 2,6-dimethyl-4-(3-nitropheny...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317776BDBM50317776(dimethyl 2,6-dimethyl-4-(2-(methylthio)phenyl)-1,4...)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317830BDBM50317830(3-cinnamyl 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)...)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317794BDBM50317794(diethyl 2-(acetoxymethyl)-6-methyl-4-(3-nitropheny...)
Affinity DataIC50: 37nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317834BDBM50317834(3-(4-(4-methoxyphenyl)butyl)5-methyl 2,6-dimethyl-...)
Affinity DataIC50: 38nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317832BDBM50317832(3-methyl 5-(4-phenylbutyl)2,6-dimethyl-4-(3-nitrop...)
Affinity DataIC50: 38nMAssay Description:Antagonist activity at rat Cav1.3 expressed in HEK293 cells assessed as inhibition of voltage pulse-induced calcium current by FLIPR calcium 4 assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Rat)
Universita' Degli Studi Di Siena

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50072816BDBM50072816(2,6-Dimethyl-4-[2-(2-nitrooxy-ethoxy)-phenyl]-1,4-...)
Affinity DataKi:  38nMAssay Description:Binding affinity for L-type [Ca2+] channels was measured through displacement of [3H]nitrendipine on rat cortex homogenates.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/9/2012
Entry Details Article
PubMed
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