Compile Data Set for Download or QSAR
Report error Found 15 of affinity data for UniProtKB/TrEMBL: P34980
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50553011BDBM50553011(CHEMBL4791261)
Affinity DataKi:  1nMAssay Description:Binding affinity to rat EP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2022
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384444BDBM50384444(CHEMBL2035510)
Affinity DataKi:  3.16nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580012BDBM50580012(CHEMBL5074870)
Affinity DataKi:  3.60nMAssay Description:Binding affinity to rat EP3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50414549BDBM50414549(CHEMBL563480)
Affinity DataKi:  6.31nMAssay Description:Inhibition of rat EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384445BDBM50384445(CHEMBL2035508)
Affinity DataKi:  7.94nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384443BDBM50384443(CHEMBL1770317)
Affinity DataKi:  10nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384446BDBM50384446(CHEMBL2035509)
Affinity DataKi:  12.6nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataKi:  18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22369BDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataKi:  41nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22369BDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataKi:  46nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50417192BDBM50417192(CHEMBL1271476)
Affinity DataKi:  158nMAssay Description:Inhibition of rat EP3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17638BDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50384442BDBM50384442(CHEMBL2035507)
Affinity DataKi:  316nMAssay Description:Antagonist activity at rat EP3 receptor expressed in human U2OS cells co-expressing Gqi5 assessed as inhibition of PGE2-induced response after 24 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50308131BDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]PGE2 from rat EP3 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22369BDBM22369(CHEMBL122 | MK 0966 | 4-(4-methanesulfonylphenyl)-...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2012
Entry Details
PubMed