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Found 20 of affinity data for UniProtKB/TrEMBL: P49773
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360481(CHEMBL1934757)
Affinity DataKi:  3.40E+4nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360480(CHEMBL1934756)
Affinity DataKi:  1.03E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360478(CHEMBL1934754)
Affinity DataKi:  1.39E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360476(CHEMBL1934752)
Affinity DataKi:  4.00E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360477(CHEMBL1934753)
Affinity DataKi:  4.57E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360479(CHEMBL1934755)
Affinity DataKi:  7.15E+5nMAssay Description:Non-competitive inhibition of human HinT1 using tryptamine 5'-adenosine phosphoramidate as substrate compound pre-incubated for 30 secs prior substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119454(CHEMBL3140272)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells using TrpAMP as substrate measured for 2 to 30 mins by fluorescenc...More data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360481(CHEMBL1934757)
Affinity DataIC50:  2.55E+4nMAssay Description:Inhibition of His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells using TrpAMP as substrate measured for 2 to 30 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50119454(CHEMBL3140272)
Affinity DataKd:  320nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50535045(CHEMBL4455776)
Affinity DataKd:  810nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50535046(CHEMBL4549820)
Affinity DataKd:  920nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50535044(CHEMBL4471567)
Affinity DataKd:  230nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50360481(CHEMBL1934757)
Affinity DataKd:  3.65E+3nMAssay Description:Binding affinity to recombinant human HINT1 by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM426061(US10513520, Compound GMP | guanosine monophosphate)
Affinity DataKd:  6.70E+4nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM426060(US10513520, Compound 7)
Affinity DataKd:  230nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM50535047(CHEMBL4468179)
Affinity DataKd:  2.90E+3nMAssay Description:Binding affinity to His-tagged human full length HINT1 expressed in Rosetta2 pLysS cells by isothermal titration calorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM426058(US10513520, Compound 5)
Affinity DataKd:  2.90E+3nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM426057(US10513520, Compound 4)
Affinity DataKd:  810nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM426056(US10513520, Compound 3)
Affinity DataKd:  3.65E+3nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine 5'-monophosphoramidase HINT1(Homo sapiens (Human))
University Of Minnesota

Curated by ChEMBL
LigandPNGBDBM426059(US10513520, Compound 6)
Affinity DataKd:  920nMAssay Description:ITC experiments were conducted on a MicroCal Auto-ITC200 system (GE Healthcare life sciences). All titration experiments were performed at 20° C. in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent