Compile Data Set for Download or QSAR
Report error Found 20 of affinity data for UniProtKB/TrEMBL: P51680
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278798BDBM50278798(CHEMBL4172635)
Affinity DataIC50: 1nMAssay Description:Antagonist activity at mouse CCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378979BDBM50378979(CHEMBL2011441)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at mouse CCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50278724BDBM50278724(CHEMBL4169247)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at mouse CCR4More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265742BDBM50265742({1'-[4-(Cycloheptylamino)-6,7-dimethoxyquinazolin-...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50243945BDBM50243945(N-cycloheptyl-6,7-dimethoxy-2-(4-(piperidin-1-yl)p...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50545778BDBM50545778(CHEMBL4637143)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at CCR4 in mouse Treg cells assessed as inhibition of CCL22-mediated chemotaxis preincubated for 30 mins followed by CCL22 additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265669BDBM50265669((1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinaz...)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245036BDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244380BDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245036BDBM50245036(N-(4-Chlorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50244380BDBM50244380(N-cycloheptyl-6,7-dimethoxy-2-(4-(pyrrolidin-1-yl)...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265748BDBM50265748((1'-{4-[(4-Chlorobenzyl)amino]-6,7-dimethoxyquinaz...)
Affinity DataIC50: 140nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50516625BDBM50516625(CHEMBL4459231)
Affinity DataIC50: 165nMAssay Description:Antagonist activity at CCR4 in anti-CD3/CD28 stimulated mouse Treg cells assessed as inhibition of CCL22-mediated chemotaxis in presence of 100% huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265670BDBM50265670(N-(4-Chlorophenyl)-6,7-dimethoxy-2-[3-(methoxymeth...)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50516626BDBM50516626(CHEMBL4475665)
Affinity DataIC50: 325nMAssay Description:Antagonist activity at CCR4 in anti-CD3/CD28 stimulated mouse Treg cells assessed as inhibition of CCL22-mediated chemotaxis in presence of 100% huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265749BDBM50265749(1'-(4-{[2-(4-Chlorophenyl)ethyl]amino}-6,7-dimetho...)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265668BDBM50265668(N-(4-chlorophenyl)-6,7-dimethoxy-2-(3-methoxy-1,4'...)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50265667BDBM50265667(1'-{4-[(4-Chlorophenyl)amino]-6,7-dimethoxyquinazo...)
Affinity DataIC50: 430nMAssay Description:Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245069BDBM50245069(N-(4-Fluorophenyl)-6,7-dimethoxy-2-(4-pyrrolidin-1...)
Affinity DataIC50: 710nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetC-C chemokine receptor type 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50245034BDBM50245034(N-(3,4-Difluorophenyl)-6,7-dimethoxy-2-(4-pyrrolid...)
Affinity DataIC50: 820nMAssay Description:Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed