Affinity DataKi: 0.0900nMAssay Description:Binding affinity for rat melanocortin-4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.390nMAssay Description:Binding affinity for rat melanocortin-4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 0.520nMAssay Description:Binding affinity for rat melanocortin-4 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Binding affinity at rat MC4RMore data for this Ligand-Target Pair
Affinity DataKi: 5.5nMAssay Description:Binding affinity at rat MC4RMore data for this Ligand-Target Pair
Affinity DataKi: 9.10nMAssay Description:Binding affinity to rat MC4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Binding affinity to rat MC4RMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Evaluated for binding affinity against rat Melanocortin-4 receptor (rMC4R) by displacing [125I]NDP-alpha-MSH radioligand expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity to rat MC4RMore data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Binding affinity to rat MC4RMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Binding affinity to rat MC4RMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition concentration (binding affinity) against rat melanocortin receptor 4 by displacement of [125I]-NDP-alpha-MSH from the human receptors expr...More data for this Ligand-Target Pair
Affinity DataEC50: 5.00E+3nMAssay Description:Concentration of compound at 50% maximum cAMP accumulation in rat melanocortin receptor (rMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at rat MC4R expressed in CHO cells assessed as cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90nMAssay Description:Functional activity as concentration of the compound at 50% maximum cAMP accumulation in rat Melanocortin-4 receptor (rMC4R)More data for this Ligand-Target Pair
Affinity DataEC50: 640nMAssay Description:Agonist activity at rat GPR40 in presence of 0.01% human serum albuminMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Agonist activity at rat MC4R expressed in CHO cells assessed as stimulation of intracellular cAMP accumulationMore data for this Ligand-Target Pair
Affinity DataEC50: 1.10nMAssay Description:Agonist activity at rat melanocortin 4 receptor expressed in CHO cells assessed as cAMP releaseMore data for this Ligand-Target Pair
Affinity DataEC50: 0.900nMAssay Description:Binding affinity to rat MC4RMore data for this Ligand-Target Pair
Affinity DataEC50: 0.5nMAssay Description:Binding affinity to rat MC4RMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at GPR40 in rat RINm cells assessed as increase glucose-stimulated insulin secretion after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 2.70E+4nMAssay Description:Agonist activity at GPR40 in rat RINm cells assessed as increase glucose-stimulated insulin secretion after 1 hr by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Affinity DataEC50: 11nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Affinity DataEC50: 3.10nMAssay Description:Experiment Method(1) Construction of Rat MC4 Receptor-Expressing VectorA rat MC4 receptor gene (GenBank Accession No.: NM_013099.2) was introduced in...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
Affinity DataEC50: 68nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
Affinity DataEC50: 95nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
Affinity DataEC50: 98nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
Affinity DataEC50: 562nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
Affinity DataEC50: 216nMAssay Description:Agonist activity at rat PK-tagged GPR40 expressed in human U2OS cells assessed as EA-tagged beta-arrestin recruitment after 90 mins in presence of 1 ...More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at rat GPR40More data for this Ligand-Target Pair
Affinity DataEC50: 28nMAssay Description:Agonist activity at rat GPR40More data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Agonist activity at rat GPR40More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Agonist activity at recombinant rat GPR40 expressed in CHOK1 cells assessed as increase in IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.490nMAssay Description:Agonist activity at recombinant rat GPR40 expressed in CHOK1 cells assessed as increase in IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.30nMAssay Description:Agonist activity at recombinant rat GPR40 expressed in CHOK1 cells assessed as increase in IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.20nMAssay Description:Agonist activity at recombinant rat GPR40 expressed in CHOK1 cells assessed as increase in IP1 accumulation measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 21nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Agonist activity at rat GPR40 assessed as increase in intracellular calcium flux by cell based FLIPR assayMore data for this Ligand-Target Pair