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Found 36 of affinity data for UniProtKB/TrEMBL: Q01984
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110309(CHEMBL14740 | Methyl-(3-piperidin-1-yl-propyl)-qui...)
Affinity DataIC50:  16nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110306((6-Piperidin-1-yl-hexyl)-(1,2,3,4-tetrahydro-acrid...)
Affinity DataIC50:  21nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110285(CHEMBL274041 | {3-[4-(3-Piperidin-1-yl-propoxy)-ph...)
Affinity DataIC50:  31nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110303((2-Piperidin-1-yl-ethyl)-(1,2,3,4-tetrahydro-acrid...)
Affinity DataIC50:  34nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110286((3-Piperidin-1-yl-propyl)-(1,2,3,4-tetrahydro-acri...)
Affinity DataIC50:  45nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110296(CHEMBL14868 | {4-[4-(3-Piperidin-1-yl-propoxy)-phe...)
Affinity DataIC50:  48nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110300(CHEMBL15056 | N-(4-(3-(piperidin-1-yl)propoxy)phen...)
Affinity DataIC50:  48nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110298(CHEMBL277113 | Ethyl-(3-piperidin-1-yl-propyl)-qui...)
Affinity DataIC50:  49nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110288(CHEMBL15153 | N-(4-(3-(piperidin-1-yl)propoxy)phen...)
Affinity DataIC50:  51nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110294((5-Piperidin-1-yl-pentyl)-quinolin-4-yl-amine; Oxa...)
Affinity DataIC50:  53nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110284((4-Piperidin-1-yl-butyl)-quinolin-4-yl-amine; Oxal...)
Affinity DataIC50:  64nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110287((3-Piperidin-1-yl-propyl)-quinolin-4-yl-amine; Oxa...)
Affinity DataIC50:  64nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110290(CHEMBL14484 | {4-[4-(3-Piperidin-1-yl-propoxy)-phe...)
Affinity DataIC50:  73nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110297((6-Piperidin-1-yl-hexyl)-quinolin-4-yl-amine; Oxal...)
Affinity DataIC50:  84nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110299(CHEMBL14754 | {3-[4-(3-Piperidin-1-yl-propoxy)-phe...)
Affinity DataIC50:  95nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  110nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110302(Acridin-9-yl-(3-piperidin-1-yl-propyl)-amine; Oxal...)
Affinity DataIC50:  110nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110311(CHEMBL276938 | {2-[4-(3-Piperidin-1-yl-propoxy)-ph...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110282((7-Chloro-quinolin-4-yl)-(7-piperidin-1-yl-heptyl)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110293(CHEMBL14860 | Methyl-(2-piperidin-1-yl-ethyl)-quin...)
Affinity DataIC50:  120nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110304((7-Chloro-quinolin-4-yl)-(5-piperidin-1-yl-pentyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110283((7-Chloro-quinolin-4-yl)-(4-piperidin-1-yl-butyl)-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110295((7-Chloro-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-...)
Affinity DataIC50:  180nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110305((7-Chloro-quinolin-4-yl)-(3-piperidin-1-yl-propyl)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110313((2-Piperidin-1-yl-ethyl)-quinolin-4-yl-amine; Oxal...)
Affinity DataIC50:  210nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110289((7-Chloro-quinolin-4-yl)-(10-piperidin-1-yl-decyl)...)
Affinity DataIC50:  220nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110301((7-Chloro-quinolin-4-yl)-(12-piperidin-1-yl-dodecy...)
Affinity DataIC50:  230nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110312((7-Chloro-quinolin-4-yl)-(8-piperidin-1-yl-octyl)-...)
Affinity DataIC50:  230nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110291((7-Chloro-quinolin-4-yl)-[4-(3-piperidin-1-yl-prop...)
Affinity DataIC50:  310nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110310((3-Methyl-quinolin-4-yl)-(6-piperidin-1-yl-hexyl)-...)
Affinity DataIC50:  340nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110281(CHEMBL14656 | Methyl-(3-piperidin-1-yl-propyl)-(1,...)
Affinity DataIC50:  360nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110308((7-Chloro-quinolin-4-yl)-{2-[4-(3-piperidin-1-yl-p...)
Affinity DataIC50:  420nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110307((3-Methyl-quinolin-4-yl)-(3-piperidin-1-yl-propyl)...)
Affinity DataIC50:  590nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50110292(CHEMBL14781 | Methyl-(2-piperidin-1-yl-ethyl)-(1,2...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of rat kidney Histamine N-Methyltransferase (HMT) activity determined by the formation of N-methylhistamineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM27213(4-[3-(4-cyclopropanecarbonylphenoxy)propyl]-1H-imi...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition against histamine-metabolizing enzyme Histamine N-methyl-transferaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine N-methyltransferase(Rattus norvegicus)
Freie UniversitäT Berlin

Curated by ChEMBL
LigandPNGBDBM50126884(1-[4-(4-Piperidin-1-ylmethyl-benzyloxy)-phenyl]-et...)
Affinity DataIC50:  1.04E+4nMAssay Description:Compound was tested against histamine N-methyl-transferase in rat brain [EC 2.1.1.8](relative weak affinity on rat enzyme)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed