Compile Data Set for Download or QSAR
maximum 50k data
Found 425 of affinity data for UniProtKB/TrEMBL: Q05469
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147315(2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-(2-m...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147297(4-Isopropyl-2-[4-(3-methoxy-phenyl)-piperazine-1-c...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50142719(CHEMBL49895 | Morpholin-4-yl-carbamic acid 4-[(4-t...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant hormone sensitive lipase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147299(4-Butyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147243(4-Isopropyl-3-methyl-2-(piperidine-1-carbonyl)-2H-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50233398(CHEMBL4063082)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147251(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50233398(CHEMBL4063082)
Affinity DataIC50:  2nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147270(3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...)
Affinity DataIC50:  2nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM121019(US8722721, 11)
Affinity DataIC50:  2.40nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147251(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147281(4-Isobutyl-3-methyl-2-(4-methyl-piperidine-1-carbo...)
Affinity DataIC50:  3nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50142713((3,4-Dihydro-1H-isoquinolin-2-yl)-carbamic acid 4-...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147257(4-(2-Ethoxy-ethyl)-3-methyl-2-(4-methyl-piperidine...)
Affinity DataIC50:  3nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50138735((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM121018(US8722721, 10)
Affinity DataIC50:  3.70nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147267(4-Cyclohexyl-3-methyl-2-(4-methyl-piperidine-1-car...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147272(4-(2-Methoxy-ethyl)-3-methyl-2-(4-m-tolyl-piperidi...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147270(3-Methyl-4-(2-phenoxy-ethyl)-2-(piperidine-1-carbo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147279(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147241(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147253(2-(4-(3-fluorophenyl)piperidine-1-carbonyl)-4-isop...)
Affinity DataIC50:  4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147245(4-Isobutyl-3-methyl-2-(4-phenyl-piperidine-1-carbo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147289(4-Isobutyl-3-methyl-2-(piperidine-1-carbonyl)-2H-i...)
Affinity DataIC50:  5nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147260(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50142731(CHEMBL49417 | [4-(Morpholin-4-ylcarbamoyloxy)-phen...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant hormone sensitive lipase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147303(4-Benzyl-3-methyl-2-(piperidine-1-carbonyl)-2H-iso...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147298(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147248(4-(2-Methoxy-ethyl)-3-methyl-2-(4-phenyl-piperidin...)
Affinity DataIC50:  5nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147234(4-Isopropyl-3-methyl-2-(4-phenyl-piperazine-1-carb...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147300(4-(4-Chloro-phenylsulfanyl)-3-methyl-2-(piperidine...)
Affinity DataIC50:  6nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147244(1-(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carbo...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147283(4-Isopropyl-3-methyl-2-(4-methyl-piperidine-1-carb...)
Affinity DataIC50:  6nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147282(3-Methyl-4-phenylsulfanyl-2-(piperidine-1-carbonyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147280(3-Methyl-2-(4-methyl-piperidine-1-carbonyl)-4-(tet...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147276(4-Cyclopentyl-3-methyl-2-(piperidine-1-carbonyl)-2...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147271(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147269(2-(3,3-Dimethyl-piperidine-1-carbonyl)-4-isopropyl...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147296(4-Butyl-3-methyl-2-(piperidine-1-carbonyl)-2H-isox...)
Affinity DataIC50:  7nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50180627(CHEMBL3814077)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human HSL expressed in Sf9 insect cells using PNPB as substrate measured after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM120365(US8703807, 1)
Affinity DataIC50:  7.70nMpH: 7.2 T: 2°CAssay Description:HSL enzyme activity was measured by a colorimetric assay using 2,3-dimercapto-1-propanol tributyrate (Aldrich, St. Louis, Mo.) as a substrate. Typica...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147259(4-Cyclopentyl-3-methyl-2-(4-phenyl-piperidine-1-ca...)
Affinity DataIC50:  8nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147262(4-Isopropyl-3-methyl-2-(thiomorpholine-4-carbonyl)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50260458(CHEMBL4063918)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 insect cells using PNPB as substrate after 5 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50233399(CHEMBL4101186)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human HSL expressed in baculovirus infected sf9 cells using PNPB as substrate after 5 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147241(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147263(4-Isopropyl-3-methyl-5-oxo-5H-isoxazole-2-carboxyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147245(4-Isobutyl-3-methyl-2-(4-phenyl-piperidine-1-carbo...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147299(4-Butyl-3-methyl-2-(4-methyl-piperidine-1-carbonyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of forskolin-stimulated lipolysis in differentiated 3T3-L1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Bayer Research Center

Curated by ChEMBL
LigandPNGBDBM50147285(4-(2-Methoxy-ethyl)-3-methyl-2-(piperidine-1-carbo...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant hormone sensitive lipase (HSL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 425 total ) | Next | Last >>
Jump to: