Compile Data Set for Download or QSAR
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Found 42 for UniProtKB: Q14285
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387083(4-(4-(1-(3-Fluoronaphthalen-2-yl)-7-oxo-3-(trifluo...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387054(1-(4-Methoxyphenyl)-6-(1-(2-oxopyrrolidin-1-yl)pip...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387080(4-(4-(1-(3-Aminobenzo[d]isoxazol-5-yl)-7-oxo-3-(tr...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387078(4-(4-(1-(6-Chloronaphthalen-2-yl)-7-oxo-3-(trifluo...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387082(4-(4-(1-(3-Fluoro-4-methoxyphenyl)-7-oxo-3-(triflu...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387050(1-(4-Methoxyphenyl)-6-(2′-oxo-[1,1′-bi...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387049(4-(4-(1-(4-Methoxyphenyl)-7-oxo-3-(trifluoromethyl...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM19023(1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-y...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387055(1-(4-Methoxyphenyl)-7-oxo-6-(2′-oxo-[1,1R...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387056(1-(4-Methoxyphenyl)-7-oxo-6-(2′-oxo-[1,1R...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387057(N′-Cyano-1-(4-methoxyphenyl)-7-oxo-6-(2̸...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387058(1-(4-Methoxyphenyl)-7-oxo-6-(1-(3-oxomorpholino)pi...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387065(1-(4-(Difluoromethoxy)phenyl)-7-oxo-6-(1-(3-oxomor...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387068(1-(4-Methoxyphenyl)-7-oxo-6-(2-oxo-[1,4′-bip...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387077(4-(4-(1-(4-(Difluoromethoxy)phenyl)-7-oxo-3-(trifl...)
Affinity DataKi: <10nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387069(1-(4-Methoxyphenyl)-N5-(1-(3-oxomorpholino)piperid...)
Affinity DataKi:  30nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387059(US9938272, Example 8a | US9938272, Example 8b)
Affinity DataKi:  30nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387085(3-(7-Oxo-6-(1-(3-oxomorpholino)piperidin-4-yl)-3-(...)
Affinity DataKi:  30nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V/Coagulation factor X/Serine/threonine-protein kinase BRSK2(Homo sapiens (Human))
North China Pharmaceutical

US Patent
LigandPNGBDBM387064(7-Oxo-6-(1-(3-oxomorpholino)piperidin-4-yl)-1-(4-(...)
Affinity DataKi:  525nMAssay Description:Prothrombinase Assay:The effect of test compounds on prothrombinase activity is measured via thrombin generation. Briefly, 12.5 μL human factor ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376425(CHEMBL1162108)
Affinity DataIC50:  1.81E+3nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376418(CHEMBL259312)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376418(CHEMBL259312)
Affinity DataIC50:  3.51E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376419(CHEMBL1162109)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376423(CHEMBL410427)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376423(CHEMBL410427)
Affinity DataIC50:  5.53E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376422(CHEMBL265687)
Affinity DataIC50:  6.71E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50:  8.55E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376422(CHEMBL265687)
Affinity DataIC50:  8.56E+3nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376421(CHEMBL410426)
Affinity DataIC50:  8.95E+3nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376422(CHEMBL265687)
Affinity DataIC50:  9.19E+3nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50423622(CHEMBL1614804)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376420(CHEMBL1162110)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376417(CHEMBL261865)
Affinity DataIC50:  1.41E+4nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50423622(CHEMBL1614804)
Affinity DataIC50:  1.57E+4nMAssay Description:Inhibition of human factor 5a light chain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376420(CHEMBL1162110)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376418(CHEMBL259312)
Affinity DataIC50:  1.86E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376417(CHEMBL261865)
Affinity DataIC50:  2.19E+4nMAssay Description:Inhibition of human recombinant factor 5a C2 domain binding to immobilized phospholipid by surface plasmon resonance assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50423622(CHEMBL1614804)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376417(CHEMBL261865)
Affinity DataIC50:  3.81E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376420(CHEMBL1162110)
Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor V(Homo sapiens (Human))
Maastricht University

Curated by ChEMBL
LigandPNGBDBM50376423(CHEMBL410427)
Affinity DataIC50:  6.29E+4nMAssay Description:Inhibition of factor 5a-mediated prothrombin activation in human plasma by prothrombinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed