Compile Data Set for Download or QSAR
maximum 50k data
Found 106 of affinity data for UniProtKB/TrEMBL: Q62928
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50308131(4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]...)
Affinity DataKi:  7.20E+3nMAssay Description:Displacement of [3H]PGE2 from rat EP2 receptor expressed in HEK293-EBNA cells by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  10nMAssay Description:Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092616(CHEMBL3586360)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293496(2-(3-((N-(4-tert-butylbenzyl)pyridine-3-sulfonamid...)
Affinity DataIC50:  50nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293493(3-(3-((N-(4-tert-butylbenzyl)pyridine-2-sulfonamid...)
Affinity DataIC50:  52nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293495(3-(3-((N-(4-tert-butylbenzyl)thiazole-2-sulfonamid...)
Affinity DataIC50:  63nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181282(5-(3-((S)-2-(4-(4-chlorophenyl)-3-hydroxybutyl)-5-...)
Affinity DataIC50:  86nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293498(7-(N-(4-(1-hydroxyhexyl)benzyl)methylsulfonamido)h...)
Affinity DataIC50:  93nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092617(CHEMBL3586309)
Affinity DataIC50:  100nMAssay Description:Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181294(5-{3-[(S)-2-(4-biphenyl-2-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataIC50:  125nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataIC50:  135nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293502(7-(N-(4-butylbenzyl)methylsulfonamido)heptanoic ac...)
Affinity DataIC50:  160nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181274(5-(3-((S)-2-((R)-4-(3-chlorophenyl)-3-hydroxybutyl...)
Affinity DataIC50:  188nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293497(7-(N-(4-hydroxynonyl)methylsulfonamido)heptanoic a...)
Affinity DataIC50:  225nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293490(3-(3-((N-(4-butylbenzyl)methylsulfonamido)methyl)p...)
Affinity DataIC50:  270nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293492(3-(3-((N-(4-tert-butylbenzyl)phenylsulfonamido)met...)
Affinity DataIC50:  278nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293503(7-(N-(biphenyl-4-ylmethyl)methylsulfonamido)heptan...)
Affinity DataIC50:  289nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50092617(CHEMBL3586309)
Affinity DataIC50:  300nMAssay Description:Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293494(2-(3-((N-(4-tert-butylbenzyl)-1-(1-methyl-1H-imida...)
Affinity DataIC50:  326nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293491(3-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)
Affinity DataIC50:  379nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181298(5-(3-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)p...)
Affinity DataIC50:  483nMAssay Description:Binding affinity to rat EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181298(5-(3-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)p...)
Affinity DataIC50:  483nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293509(4-(2-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)
Affinity DataIC50:  494nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293501(7-(N-(4-(1-hydroxypentyl)benzyl)methylsulfonamido)...)
Affinity DataIC50:  502nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293504(7-(N-(4-tert-butylbenzyl)methylsulfonamido)heptano...)
Affinity DataIC50:  590nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293500(7-(N-(4-hexanoylbenzyl)methylsulfonamido)heptanoic...)
Affinity DataIC50:  636nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181289(5-(3-((S)-2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-...)
Affinity DataIC50:  640nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293510(4-(4-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)
Affinity DataIC50:  654nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181296(5-(3-((S)-2-(3-hydroxy-4-phenylbutyl)-5-oxopyrroli...)
Affinity DataIC50:  690nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293505(2-(4-(N-(4-butylbenzyl)methylsulfonamido)butoxy)ac...)
Affinity DataIC50:  701nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293489(2-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)
Affinity DataIC50:  792nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293507(2-(4-(2-(N-(4-butylbenzyl)methylsulfonamido)ethyl)...)
Affinity DataIC50:  833nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293488(6-(N-(4-hydroxynonyl)methylsulfonamido)hexanoic ac...)
Affinity DataIC50:  910nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181280(5-(3-((S)-2-(4-(4-ethylphenyl)-3-hydroxybutyl)-5-o...)
Affinity DataIC50:  1.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181286(5-(3-((S)-2-((R)-4-(4-fluorophenyl)-3-hydroxybutyl...)
Affinity DataIC50:  1.21E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293499(7-(N-(4-hydroxy-6-methylheptyl)methylsulfonamido)h...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50293506(3-(3-(N-(4-butylbenzyl)methylsulfonamido)propoxy)b...)
Affinity DataIC50:  3.13E+3nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181272(4-(3-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)p...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181273(7-[(S)-2-((R)-4-biphenyl-3-yl-3-hydroxy-butyl)-5-o...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181276(7-((S)-2-(3-hydroxy-4-(3-phenoxyphenyl)butyl)-5-ox...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181279(7-(2-(4-(3-chlorophenyl)-3-hydroxybutyl)-5-oxopyrr...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181275(7-((S)-2-((R)-4-(3-cyanophenyl)-3-hydroxybutyl)-5-...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181281(4-(3-(2-(4-(3-fluorophenyl)-3-hydroxybutyl)-5-oxop...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181287(7-((S)-2-((R)-3-hydroxy-4-(3-hydroxyphenyl)butyl)-...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181293(7-((S)-2-((R)-3-hydroxy-4-(3-(methoxymethyl)phenyl...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181292(7-(2-(3-hydroxy-5-phenylpentyl)-5-oxopyrrolidin-1-...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181271(7-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethoxy)phe...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181285(4-(3-(2-(3-hydroxy-4-(3-phenoxyphenyl)butyl)-5-oxo...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Rattus norvegicus)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50181278(7-((S)-2-((R)-3-hydroxy-4-(3-(2-methoxyethyl)pheny...)
Affinity DataIC50: >3.20E+3nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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