Compile Data Set for Download or QSAR
Report error Found 106 of affinity data for UniProtKB/TrEMBL: Q62928
LigandChemical structure of BindingDB Monomer ID 50293492BDBM50293492(3-(3-((N-(4-tert-butylbenzyl)phenylsulfonamido)met...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35847BDBM35847(DINOPROSTONE | [3H]Prostaglandin E2 | prostaglandi...)
Affinity DataEC50:  0.200nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293496BDBM50293496(2-(3-((N-(4-tert-butylbenzyl)pyridine-3-sulfonamid...)
Affinity DataEC50:  0.300nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293495BDBM50293495(3-(3-((N-(4-tert-butylbenzyl)thiazole-2-sulfonamid...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293493BDBM50293493(3-(3-((N-(4-tert-butylbenzyl)pyridine-2-sulfonamid...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35847BDBM35847(DINOPROSTONE | [3H]Prostaglandin E2 | prostaglandi...)
Affinity DataIC50: 5.20nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50092616BDBM50092616(CHEMBL3586360)
Affinity DataIC50: 10nMAssay Description:Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35847BDBM35847(DINOPROSTONE | [3H]Prostaglandin E2 | prostaglandi...)
Affinity DataEC50:  19nMAssay Description:Agonist activity at rat EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50092616BDBM50092616(CHEMBL3586360)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293490BDBM50293490(3-(3-((N-(4-butylbenzyl)methylsulfonamido)methyl)p...)
Affinity DataEC50:  34.4nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293498BDBM50293498(7-(N-(4-(1-hydroxyhexyl)benzyl)methylsulfonamido)h...)
Affinity DataEC50:  44nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293491BDBM50293491(3-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)
Affinity DataEC50:  48nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293496BDBM50293496(2-(3-((N-(4-tert-butylbenzyl)pyridine-3-sulfonamid...)
Affinity DataIC50: 50nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293493BDBM50293493(3-(3-((N-(4-tert-butylbenzyl)pyridine-2-sulfonamid...)
Affinity DataIC50: 52nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293494BDBM50293494(2-(3-((N-(4-tert-butylbenzyl)-1-(1-methyl-1H-imida...)
Affinity DataEC50:  58nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293495BDBM50293495(3-(3-((N-(4-tert-butylbenzyl)thiazole-2-sulfonamid...)
Affinity DataIC50: 63nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181282BDBM50181282(5-(3-((S)-2-(4-(4-chlorophenyl)-3-hydroxybutyl)-5-...)
Affinity DataIC50: 86nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50360626BDBM50360626(CHEMBL1933722)
Affinity DataEC50:  90nMAssay Description:Agonist activity at rat EP2 receptor expressed in CHO cells assessed as cAMP production after 10 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50360626BDBM50360626(CHEMBL1933722)
Affinity DataEC50:  90nMAssay Description:Agonist activity at rat EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293498BDBM50293498(7-(N-(4-(1-hydroxyhexyl)benzyl)methylsulfonamido)h...)
Affinity DataIC50: 93nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293502BDBM50293502(7-(N-(4-butylbenzyl)methylsulfonamido)heptanoic ac...)
Affinity DataEC50:  94nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50092617BDBM50092617(CHEMBL3586309)
Affinity DataIC50: 100nMAssay Description:Displacement of [3H]-PGE2 from rat EP2 receptor overexpressed in human ECV304 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293509BDBM50293509(4-(2-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)
Affinity DataEC50:  103nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181294BDBM50181294(5-{3-[(S)-2-(4-biphenyl-2-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataIC50: 125nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293497BDBM50293497(7-(N-(4-hydroxynonyl)methylsulfonamido)heptanoic a...)
Affinity DataEC50:  134nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181290BDBM50181290(5-{3-[(S)-2-(4-biphenyl-3-yl-3-hydroxy-butyl)-5-ox...)
Affinity DataIC50: 135nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293502BDBM50293502(7-(N-(4-butylbenzyl)methylsulfonamido)heptanoic ac...)
Affinity DataIC50: 160nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181274BDBM50181274(5-(3-((S)-2-((R)-4-(3-chlorophenyl)-3-hydroxybutyl...)
Affinity DataIC50: 188nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293489BDBM50293489(2-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)
Affinity DataEC50:  203nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293497BDBM50293497(7-(N-(4-hydroxynonyl)methylsulfonamido)heptanoic a...)
Affinity DataIC50: 225nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50366137BDBM50366137(CHEMBL1957436)
Affinity DataEC50:  260nMAssay Description:Agonist activity at rat EP2 receptor expressed in CHO cells assessed as cAMP production after 10 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50366137BDBM50366137(CHEMBL1957436)
Affinity DataEC50:  260nMAssay Description:Agonist activity at rat EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293490BDBM50293490(3-(3-((N-(4-butylbenzyl)methylsulfonamido)methyl)p...)
Affinity DataIC50: 270nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293492BDBM50293492(3-(3-((N-(4-tert-butylbenzyl)phenylsulfonamido)met...)
Affinity DataIC50: 278nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293503BDBM50293503(7-(N-(biphenyl-4-ylmethyl)methylsulfonamido)heptan...)
Affinity DataIC50: 289nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50092617BDBM50092617(CHEMBL3586309)
Affinity DataIC50: 300nMAssay Description:Antagonist activity at rat EP2 receptor overexpressed in human ECV304 cells assessed as inhibition of prostaglandin E2-induced cAMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293494BDBM50293494(2-(3-((N-(4-tert-butylbenzyl)-1-(1-methyl-1H-imida...)
Affinity DataIC50: 326nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293491BDBM50293491(3-(3-((N-(4-tert-butylbenzyl)methylsulfonamido)met...)
Affinity DataIC50: 379nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50385128BDBM50385128(CHEMBL2036318)
Affinity DataEC50:  380nMAssay Description:Agonist activity at rat EP2 receptor expressed in CHO cells assessed as cAMP production after 10 mins by radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293505BDBM50293505(2-(4-(N-(4-butylbenzyl)methylsulfonamido)butoxy)ac...)
Affinity DataEC50:  407nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293507BDBM50293507(2-(4-(2-(N-(4-butylbenzyl)methylsulfonamido)ethyl)...)
Affinity DataEC50:  413nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293501BDBM50293501(7-(N-(4-(1-hydroxypentyl)benzyl)methylsulfonamido)...)
Affinity DataEC50:  423nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293503BDBM50293503(7-(N-(biphenyl-4-ylmethyl)methylsulfonamido)heptan...)
Affinity DataEC50:  457nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181298BDBM50181298(5-(3-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)p...)
Affinity DataIC50: 483nMAssay Description:Binding affinity to rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50181298BDBM50181298(5-(3-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)p...)
Affinity DataIC50: 483nMAssay Description:Binding affinity to rat EP2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293509BDBM50293509(4-(2-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)
Affinity DataIC50: 494nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293501BDBM50293501(7-(N-(4-(1-hydroxypentyl)benzyl)methylsulfonamido)...)
Affinity DataIC50: 502nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293510BDBM50293510(4-(4-(N-(4-butylbenzyl)methylsulfonamido)phenyl)bu...)
Affinity DataEC50:  587nMAssay Description:Agonist activity against rat EP2 receptor expressed in HEK293 cells assessed as stimulation of cAMP releaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293504BDBM50293504(7-(N-(4-tert-butylbenzyl)methylsulfonamido)heptano...)
Affinity DataIC50: 590nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50293500BDBM50293500(7-(N-(4-hexanoylbenzyl)methylsulfonamido)heptanoic...)
Affinity DataIC50: 636nMAssay Description:Inhibition of rat EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
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